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高频超声在高尿酸血症患者关节检测的应用价值 被引量:5

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摘要 目的 探讨高频超声在高尿酸血症患者关节检测中的应用价值.方法 随机抽取高尿酸血症患者120人,痛风性关节炎(GA组)22人、无症状高尿酸血症(AH组)98人.检测其血尿酸水平;使用高频超声检测两组患者双侧第一跖趾关节、踝关节、膝关节,比较两组关节超声图像,总结两组患者关节病变情况、声像图特点.结果 两组患者血尿酸水平比较差异无统计学意义(P=0.17),GA组病变关节92个,AH组病变关节64个,关节病变率差异有统计学意义(P=0.000).高尿酸血症关节病变特异性声像图包括“双轮廓”征、滑膜或肌腱附着处晶体沉积、痛风石,其中“双轮廓”征发生率最高;非特异性声像图包括关节积液、滑膜增厚及血流、骨侵蚀.第一跖趾关节发病率最高,与踝、膝关节比较差异有统计学意义(P<0.05).结论 高尿酸血症关节病变具有一定的特异性超声表现,高频超声能明确关节病变的部位、类型及病变程度,无症状者可较临床早期发现关节病变,具有一定的临床应用价值.
作者 陈乐
出处 《国际医药卫生导报》 2015年第11期1578-1581,共4页 International Medicine and Health Guidance News
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参考文献12

  • 1Puig JG, De Miguel E, Castillo MC, et al.Asymptomatic hyperuricemia: impact of ultrasonography[J].Nucleosides Nueleotides Nucleic Acids, 2008, 27 (6) : 592-595.
  • 2胡麦果,李拾林,吕国荣,刘显兰,吴家祥.高频超声在无症状高尿酸血症检测中的应用价值[J].中华超声影像学杂志,2014,23(1):49-53. 被引量:20
  • 3陈禹,叶迅.痛风性关节炎在高频超声下的特异性改变和非特异性改变[J].菏泽医学专科学校学报,2013,25(4):9-12. 被引量:5
  • 4Thiele RG, Schlesinger N.Diagnosis of gout by ultrasound [J]. Rheumatology, 2007, 46 (7) : 1116-1121.
  • 5曹君妍,任杰,黄冬梅,郑荣琴,王巧缘.痛风性关节炎的超声表现[J].中华超声影像学杂志,2011,20(12):1051-1054. 被引量:26
  • 6Scheel AK, Hermann KG, Kahler E, et al. A novel uhrasonographic synovitis scoring system suitable for analyzing finger joint inflammation in rheumatoid arlhritis[J].Arthdtis Rheum, 2005, 52 ( 3 ) : 733-743.
  • 7De Avila Fernandes E, Kubota ES, Sandim GB, et al. Ultrasound featmas of tnphi in chronic tophaceous gout[J].Skeletal Radiol, 201 1, 40(3) : 309-315.
  • 8De Miguel E, Ptaig JG, Castillo C, et al. Diagnosis of gout in patients with asymptomatic hyperuricaemia: a pilot uhrasound study[J]. Ann Rheum Dis, 2012, 71 ( 1 ) : 157-158.
  • 9Gutierrez M, Hilippncci E, Salaffi F, et al. The current role of ultrasound in the assessment of crystal-related arthropathies[J].R eumatismo, 2009, 61 (3) : 216-221.
  • 10Perez-Ruiz F, Martin I, Canteli B. Uhrasonographic measurement of tophi as an outcome measure for chronic gout[J]. J Rhemnatol, 2007, 34 (9) : 1888-1893.

二级参考文献70

  • 1杜国庆,王学梅,董宪普,薛竟宜.膝关节滑膜病变的高频超声与关节镜对照研究[J].中国超声医学杂志,2004,20(10):780-783. 被引量:11
  • 2McCarty DJ, Hollander JL. Identification of urate crystals in gouty synovial fluid. Ann Intern Med, 1961,54:452-460.
  • 3Ryckman C, McColl SR, Vandal K, et aI. Role of S100A8 and S100A9 in neutrophil recruitment in response to monosodium urate monohydrate crystals in the air 2 pouch model of acute gouty arthritis. Art hritis Rheum, 2003,48:2310-2320.
  • 4Inokuchi T, Moriwaki Y, Tsutsui H, et al. Plasma interleukin (IL)-18 (interferon-v-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18. Cytokine, 2006, 33:21-27.
  • 5Schlesinger N,Thiele RG. The pathogenesis of bone erosions in gouty arthritis. Ann Rheum Dis,2010,69: 1907-1912.
  • 6Balbir-C-urman A, Nahir AM. Braun-Moscovici Y, et al. Sonographic features of a tophaceous nodule. Isr Med Assoe J, 2005,7: 746-747.
  • 7Thiele RG, Schlesinger N. Diagnosis of gout by ultrasound. Rheumatology, 2007,46 : 1116-1121.
  • 8Wallace SL,Robinson H, Masi AT, et al. Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum 1977,2 : 895-900.
  • 9Backhaus M,Burmester GR,Gerber T,et al.Guidelines for musculoskeletal ultrasound in rheumatology.Ann Rheum Dis,2001,60:641-649.
  • 10Grahame R,Scott JT.Clinical survey of 354 patients with gout.Ann Rheum Dis,1970,29:461-468.

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