摘要
目的:为围术期抗菌药物的合理预防使用提供参考。方法:抽取我院2013年1-12月Ⅰ类切口手术出院病历2 421份,进行围术期预防用药的回顾性调查,分析抗菌药物使用率、给药时机、用药疗程及其具体不合理使用情况等。结果:Ⅰ类切口手术围术期预防使用抗菌药物的患者有439例,占18.13%。其中,第一代头孢菌素使用率为81.65%(356/439),林可霉素类使用率为7.57%(33/439)。术前0.5-2 h抗菌药物的使用率为97.27%(427/439)。用药疗程控制在术后48 h内的病例占60.36%(265/439)。不合理用药率为10.57%(256/2 421),包括用药疗程过长(7.18%)、抗菌药物选择不合理(2.02%)、用法用量不合理(0.50%)、给药时机不合理(0.50%)、无适应证用药(0.37%)。结论:我院Ⅰ类切口手术围术期抗菌药物的预防使用基本合理,但仍存在不重视适应证、药物选择不合理、用药疗程过长等问题,尤其还存在多种不合理现象同时出现的情况。
OBJECTIVE: To provide reference for the rational perioperative prophylactic use of antibiotics. METHODS: Total- ly 2 421 cases with type I incision operation in our hospital during Jan.-Dec. 2013 were collected and retrospectively analyzes the utilization rate, administration time, medication course and specific irrational use. RESULTS: There were totally 439 patients with perioperative prophylactic use of antibiotics in type I incision operation, accounting for 18.13%. The utilization rate of first-generation cephalosporins was 81.65% (356/439) and the clindamycin was 7.57% (33/439). The rate of antibiotics within 0.5-2 h before operation was 97.27% (427/439). 60.36% (265/439) of antibiotic treatment was finished within 48 h after operation. The irrational drug use rate was 10.57% (256/2 421) , including long course of treatment (7.18%) , unreasonable selection of antibiotics (2.02%) , unreasonable usage and dosage (0.50%) , unreasonable administration time (0.50%) and no drugs for indication (0.37 % ). CONCLUSIONS: The perioperative prophylactic use of antibiotics for type I incision operation in our hospital is basically raional, however, there were still irrationalities, including take no account of indication, irrational drug selection, too long medi- cation course, etc. especially, various irrationalities happen at the same time.
出处
《中国药房》
CAS
北大核心
2015年第17期2327-2330,共4页
China Pharmacy
关键词
Ⅰ类切口
围术期
抗菌药物
Type I incision
Perioperative period
Antibiotics