核磁共振联合超声在胎儿侧脑室扩张中的诊断价值

The diagnostic value of magnetic resonance image in combination with ultrasound in fetal expansion of the lateral ventricle

目的探讨核磁共振与超声在胎儿侧脑室扩张(Expansion of the lateral ventricle)中的诊断价值。方法经超声检查怀疑胎儿侧脑室扩张的孕妇72例,在系统超声检查后48小时内进行胎儿MRI检查。根据侧脑室扩张程度分为三组,10-12mm组,12-15mm组,>15mm组。将MRI、超声、随访结果进行对照比较研究。结果 72名孕妇共检查出胎儿72例,MRI证实胎儿侧脑室扩张68例,占超声诊断的94.4%(68/72),合并中枢神经其他异常者10例,其中胼胝体缺如或发育不良4例,脑室周围白质软化3例,小脑发育不良1例,Dandy-Walke2例,胎儿侧脑室增宽>15mm组合并中枢神经系统疾病均较10-12mm组与12-15mm组高(P<0.05),13-15mm组比10-12mm组高(P<0.05)。检出超声漏诊合并胼胝体缺如或发育不良2例,合并Dandy-Walker畸形畸形1例。结论核磁检查对胎儿侧脑室扩张的诊断价值明显高于超声,有助于明确诊断胎儿侧脑室扩张和合并畸形的诊断。

Objective： To explore the diagnostic value of magnetic resonance image （MRI） in combination with ultrasound （US） in fetal expansion of the lateral ventricle. Methods： Seventy-two pregnant women were suspected expansion of the lateral ventricle by by prenatal US.MRI were exeamed in 48 hours after US. All ventricles of fetuses were measured and classified into 4 groups.- 10-12mm, 12-15mm, 〉15mm.The results of MRI and US were compared with following up dams. Results： Seventy- two fetuses were detected in 72 pregnant women. Sixtey-eighten fetuses were confirmed expansion of the lateral ventricle with MRI in 72 casess, ten fetus were found additional central nervous system （CNS） abnormalities.Four fetuses were confirmed agenesis of corpus callosum （ACC） , three fetuses were confirmed PVL, one fetus was cerebeUar hypoplasia, two fetus was Dandy- Walker abnormality. MRI demonstrated more associated abnormalities than US in 2 fetuses, two was ACC, oner was Dandy- Walker abnormality. Conclusion.. MRI is superior to US in the diagnosis of fetal expansion of the lateral ventricle, better show the combined brain malformation of fetal expansion of the lateral ventricle.