不同空腹血糖水平与非酒精性脂肪性肝病的相关性研究

The relationship of fasting plasma glucose level and nonalcoholic fatty liver disease

目的探讨不同FPG水平与非酒精性脂肪性肝病（NAFLD）的相关性。方法选取7896名研究对象进行统一问卷调查、血液生化和肝脏超声检查,根据FPG水平将研究对象分为NGT、IFG和T2DM组,分析NAFLD影响因素。结果NGT、IFG、T2DM组NAFLD检出率分别为43.0%、63.0%和67.6%,IFG、T2DM组发生NAFLD的OR值分别是NGT组的1.31、1.77倍（95%CI：1.07~1.60、1.42~2.20,P〈0.01）。结论 IFG和T2DM是发生NAFLD的独立危险因素。

Objective To explore the relationship of FPG level and nonalcoholic fatty liver disease（NAFLD）.Methods 7896 subjects accepted questionnaire survey,blood biochemical test and liver ultrasound examination.According to FPG level,the subjects were divided into normal FPG（NGT）group,IFG group and T2 DM group.The risk factors of NAFLD were analyzed.Results The proportion of NAFLD in NGT group,IFG group and T2 DM group was 43.0%,63.0% and 67.6%.Compared with NGT group,IFG group and T2 DM group were significantly associated with higher risk of NAFLD（OR=1.31,1.77,95%CI：1.07~1.60,1.42~2.20,P〈0.01）.Conclusion IFG and T2 DM are independent risk factors for NAFLD.