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病原微生物感染的蛋白质组学研究

A Proteomic View of Host-pathogen Interactions and Infection Biology
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摘要 基于质谱的蛋白质组学在近20年有巨大的发展。在其应用中,病原微生物和与感染相关的蛋白质组学具有重要科学意义,体系复杂度又相对较小,一直受到广泛关注并有较快发展。本文从感染中病原微生物和宿主的蛋白质组学两方面入手,简要综述应用蛋白质组学研究感染过程的相关工作,着重介绍该领域近几年的主要进展,并对其发展做出展望。 MS-based proteomics has undergone rapid advancements in recent years. As infectious diseases cause millions of death each year, it has become increasingly important to study host-pathogen interactions on the mo- lecular level. Recently, proteomic analyses of pathogens and their mammalian host have received widespread atten- tions. Here we review the major progress made in this area within the last decade.
出处 《大学化学》 CAS 2015年第3期3-8,共6页 University Chemistry
关键词 蛋白质组学 质谱 病原微生物 宿主 感染 Proteomics Mass spectrometry Pathogen Host Infection
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