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肠道菌群与疾病的关系 被引量:8

The relationship of gut microbes and disease
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摘要 人类体内的肠道菌群与某些疾病的发生、发展有着重要的关联。研究表明肠道菌群不仅与肠癌、胃癌、肝癌和乳腺癌等癌症的发病有关,还与肥胖症和糖尿病的发病有着密切的关联。肥胖症和糖尿病均属于代谢性疾病,并伴有持续低度炎症。肠道菌群参与机体的能量代谢和储存,菌群失调产生内毒素引发机体炎症等,因此,肠道菌群从多方面参与肥胖症和糖尿病的病程发展。 There is an important link between gut microbes and the development of some diseases. Some studies have shown that gut microbes is related to the onset of cancer,such as colon cancer,gastric cancer,liver cancer and breast cancer,and it also influence the development of obesity and diabetes. Obesity and diabetes are metabolic diseases and accompanied by persistent and low- grade inflammation. Gut microbes participate in metabolism and storage of body's energy. Endotoxin,produced in dysbacteria,can trigger the body's inflammation. Therefore,gut microbes take part in the progression of obesity and diabetes in many directions.
出处 《药学研究》 CAS 2015年第6期353-356,共4页 Journal of Pharmaceutical Research
基金 中国博士后科学基金(No.2013M540306)
关键词 胃肠道菌 癌症 肥胖症 糖尿病 Gut microbes Cancer Obesity Diabetes
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