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幼年特发性关节炎并发葡萄膜炎的治疗新进展 被引量:1

Treatment advances in uveitis associated with juvenile idiopathic arthritis
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摘要 近年来,幼年特发性关节炎并发葡萄膜炎的治疗取得了一定的进展,但由于疾病的复发率较高,病情较复杂,使该病较难控制。现有药物的副作用较多,难以有效地控制疾病的发展,探索新的治疗方案是目前的研究热点。本文我们就目前已知的治疗方案以及未来可能应用于临床的治疗方法进行综述。 In recent years, some progresses had been made in the treatment of uve- itis associated with juvenile idiopathic arthritis, because of its aggressiveness and fre- quent complications, uveitis associated with juvenile idiopathic arthritis remains a chal- lenging disease to control. Because of the side effects of existing drugs are more, it is difficult to effectively control the progress of the disease. This paper reviews the present and possible treatments of uveitis associated with juvenile idiopathic arthritis.
出处 《眼科新进展》 CAS 北大核心 2015年第6期585-587,共3页 Recent Advances in Ophthalmology
基金 国家自然科学基金青年科学基金资助(编号:81201184)~~
关键词 幼年特发性关节炎 葡萄膜炎 皮质类固醇 免疫调节药物 生物制剂 juvenile idiopathic arthritis uveitis corticosteroids imraunomodulato-ry drugs biological treatment microRNA
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参考文献31

  • 1Carvounis PE, Herman DC, Cha S, Burke JP. Incidence and out- comes of uveitis in juvenile rheumatoid arthritis, a synthesis of the literature[ J ]. Graefes Arch Clin Exp Ophthalmol,2006 ,244 (3) :281-290.
  • 2Yu HH, Chen PC, Wang LC, Lee JH, IAn YT, Yang YH, et al. Ju- venile idiopathic arthritis-associated uveitis:a nationwide popu- lation-based study in taiwan [ J ]. PLoS One, 2013,8 ( 8 ) : e70625.
  • 3Rahi AH, Kanski J J, Fielder A. Immunoglobulins and antinu- clear antibodies in aqueous humour from patients with juvenile "rheumatoid" arthritis ( Still' s disease ) [ J ]. Trans Ophthalmol Soc UK,1977,97(3) :217-222.
  • 4Thorne JE, Woreta FA, Dunn JP, Jabs DA. Risk of cataract de- velopment among children with juvenile idiopathic arthritis-re- lated uveitis treated with topical corticosteroids [ J ]. Ophthal- mology,2010,117(7) : 1436-1441.
  • 5Simonini G, Paudyal P,Jones GT, Cimaz R, Macfarlane GJ. Cur- rent evidence of methotrexate efficacy in childhood chronic u- veitis: a systematic review and meta analysis approach [ J ]. Rheumatology(Oxford) ,2013,52 ( 5 ) :825-831.
  • 6Albarouni M, Becker I, Horneff G. Predictors of response to methotrexate in juvenile idiopathic arthritis [ J]. Pediatr Rheu- matol Online J,2014,12( 1 ) :35.
  • 7Goebel JC, Roesel M, Heinz C, Michels H, Ganser G, Heiligen- hans A. Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis [ J ]. Br J Ophthalmol, 2011,95 (2) :209-213.
  • 8Doycheva D, Deuter C, Stuebiger N, Biester S, Ziethut M. Myco- phenolate mofetil in the treatment of uveitis in children[ J ]. Br J Ophthaimol,2007,91 (2) :180-184.
  • 9Chang PY, Giuliari GP, Shaikh M, Thakutia P, Makhoul D, Foster CS, et al. Mycophenolate mofetil monothempy in the manage- ment of paediatric uveitis[ J]. Eye (Lond) ,2011,25 (4) :427- 435.
  • 10Sflverman E. Leflunomide or methotrexate for juvenile rheuma- toid arthritis[ J]. N Engl J Med ,2005,352 ( 16 ) : 1655-1666.

二级参考文献44

  • 1Kojima M, Kojima T, Ishiguro N, et al. Psychosocial factors, disease status ,and quality of life in patients with rheumatoid arthritis[ J]. J Psychosom Res,2009 ,67 (5) :425-431.
  • 2Karakoe M, Batmaz [, Sariyildiz M A,et al. The relationship of met- abolic syndrome with disease activity and the functional status in patients with rheumatoid arthritis[J]. J Clin Med Res, 2012,4 (4) :279-285.
  • 3Chung C P, Oeser A, Solus J F,et al. Inflammation-associated insu- lin resistance: differential effects in rheumatoid arthritis and sys- temic lupus erythematosus define potential mechanisms[J]. Arthri- tis Rheum,2008,58(7) :2105-2112.
  • 4Cheal K L,Abbasi F, Lamendola C,et al. Relationship to insulin resistance of the adult treatment panel iii diagnostic criteria for identification of the metabolic syndrome [ J ]. Diabetes, 2004, 53 (5) :1195-1200.
  • 5Shahin D, Eltoraby E, Mesbah A, et al. Insulin resistance in early untreated rheumatoid arthritis patients[J]. Clin Biochem,2010,43 (7/8) :661465.
  • 6Slagakis I, Bertsias G, Karvounaris S, et al. Anti-tumor necrosis fac- tor therapy improves insulin resistance, beta cell function and insu- lin signaling in active rheumatoid arthritis patients with high insu- lin resistance[J]. Arthritis Res Ther ,2012,14 ( 3 ) : R141.
  • 7Myasoedova E, Crowson C S, Kremers H M,et al. Lipid paradox in rheumatoid arthritis:the impact of serum lipid measures and sys- temic inilammation on the risk of cardiovascular disease [J]. Ann Rheum Dis ,2011,70 ( 3 ) :482-487.
  • 8Myasoedova E, Crowson C S, Kremers H M,et al. Total cholesterol and LDL levels decrease before rheumatoid arthritis [J]. Ann Rheum Dis,2010,69(7) :1310-1314.
  • 9Choy E, Sattar N. Interpreting lipid levels in the context of high- grade inflammatory states with a focus on rheumatoid arthritis:a challenge to conventional cardiovascular risk actions [J]. Ann Rheum Dis,2009,68(4) :460-469.
  • 10Choi H K, Seeger J D. Lipid profiles anmng us elderly with untreated rheumatoid arthritis:the third national health and nutrition examination survey[ J ]. J Rheumatol,2005,32( 12 ) :2311-2316.

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