期刊文献+

羟苯磺酸钙致中毒性表皮坏死松解症1例 被引量:4

A Case of Calcium Dobesilate-induced Toxic Epidermal Necrolysis
下载PDF
导出
摘要 报告1例中毒性表皮坏死松解症。患者女,71岁。全身红斑、水疱、表皮剥脱伴疼痛1d。全身表皮剥脱面积>30%,伴有外阴黏膜损害。可疑致敏药物为羟苯磺酸钙。予大剂量甲泼尼龙和静脉注射用人免疫球蛋白治疗无效,死亡。 A case of toxic epidermal necrolysis (TEN) is reported. A 71-year-old woman presented with generalized painful erythemas, vesicles and exfoliated skin for one day. Physical examination showed an over 30% of body surface with epidermal exfoliation. Vulvar mucosa was also involved. Calcium dobesilate was suspected to be the allergen. High dose of methylprednisolone and intravenous immunoglobulins( IV Ig) were ineffec- tive and the patient died later.
出处 《中国皮肤性病学杂志》 CAS CSCD 北大核心 2015年第6期615-616,共2页 The Chinese Journal of Dermatovenereology
关键词 药疹 中毒性表皮坏死松解症 羟苯磺酸钙 Drug eruption Toxic epidermal necrolysis Calcium dobesilate
  • 相关文献

参考文献9

二级参考文献29

  • 1Philippe Paquet, GErald E. Pierard. New insight in toxic epidermal necrolysis ( Lyell's syndrome ). Drug Saf, 2010, 33 ( 3 ): 189-212.
  • 2Nathanael S. Home, Archana R. Naravan Rose-Marie et al. Toxic epidermal necrolysis in systemic lupus erythematosus. Autoimmunity Review. 2006(5 ): 160-164.
  • 3Meiss F, Helmbold P. Meykadeh V, et al. Overlap of acute generalized exanthematous pustulosis and toxic epidermal necrolysis: response to antitumour necrosis factor-or antibody infliximab: report of three cases, J Eur Acad Dermatol Venereol, 2007. 21: 717-719.
  • 4Gareia-Doval I, LeCleach L, Bocquet H, et al. Toxic epidermal necrolysis and Stevens-Johnson syndrome: does early withdrawal of causative drugs decrease the risk of death?[J]. Arch Dermatol, 2000, 136(3): 323-327.
  • 5Pereira FA, Mudgil AV, Rosmarin DM. Toxic epidermal necrolysis[J]. J Am Acad Dermatol, 2007, 56(2): 181-200.
  • 6Chave TA, Mortimer N J, Sladden M J, et al. Toxic epidermal necrolysis: current evidence, practical management and future Directions[J]. Br J Dermatol, 2005, 153(2): 241-253.
  • 7Dalli RL, Kumar R, Kennedy P, et al. Toxic epidermal necrolysis/Stevens-Johnson syndrome: current trends in Management[J]. ANZ J Surg, 2007, 77(8): 671-676.
  • 8Paquet P, Pierard GE, Quatresooz P. Novel treatments for druginduced toxic epidermal necrolysis (Lyell's syndrome) [J]. Int Arch Allergy Immunol, 2005, 136(3): 205-216.
  • 9Gue6gan S, Bastuji-Garin S, Poszepczynska-Guigne E, et al. Performance of the SCORTEN during the first five days of hospitalization to predict the prognosis of epidermal necrolysis[J]. J Invest Dermatol, 2006, 126(2): 272-276.
  • 10Kardaun SH, Jonkman MF. Dexamethasone pulse therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis [J]. Acta Derm Venereol, 2007, 87(2): 144-148.

共引文献35

同被引文献35

引证文献4

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部