纵隔海绵状血管瘤10例临床分析

Cavernous hemangioma of mediastinum： a report of 10 cases

目的 探讨纵隔海绵状血管瘤（CHM）的临床特点,诊断治疗和预后.方法 回顾性分析1999至2014年期间中国医学科学院肿瘤医院收治的10例纵隔海绵状血管瘤患者的临床病理资料,并复习文献.结果 10例患者就诊时临床症状体征无特异性,影像学检查可见纵隔囊性肿块,但术前不能确诊.通过手术完整切除肿瘤,病理确诊为CHM.术后随访所有患者均无复发、死亡,最长随访时间为12年.结论 纵隔海绵状血管瘤极易误诊.如CT发现纵隔低密度肿物或肿物内有钙化,应警惕CHM可能.手术中肿瘤典型的外观特点结合穿刺和冰冻病理可明确诊断.手术完整切除是本病的首选治疗方法.

Objective To explore the clinical characteristics,diagnosis,treatment and prognosis of cavernous hemangioma of mediastinum （CHM）.Methods Retrospective analyses were performed for the clinical data of 10 CHM patients at our hospital along with a literature review.Results The clinical symptoms and signs were nonspecific.Although computed tomography （CT） showed mediastinal cystic mass,a definite diagnosis could not be reached.Complete surgical excision was performed with a pathological confirmation of CHM.Neither recurrence nor mortality occurred during the postoperative followup up to 12 years.Conclusions CHM is rare and frequently misdiagnosed.Hypodensity or calcification inside mass on CT is diagnostic.A definite diagnosis is dependent upon typical tumor appearances and pathological report of puncture biopsy.Excision is an effective cure with a fair prognosis.