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梅毒细胞免疫机制研究进展 被引量：4

Update of cellular immune mechanism in syphilis
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摘要 梅毒发病以及病程的迁延与机体细胞免疫机制有着重要关联,主要包括Th1/Th2反应的平衡,CD4^+和CD8^+T细胞,Th7和Th22,细胞因子(IL-33、IL-35、IL-37、IL-38),本文对其作一综述。 The onset of syphilis is correlated with the cellular immune mechanism, including Thl/Th2 bal- ance, and involvement of CD4＋ and CD8＋ T cells, Thl7 cells and Th22 ceils, cytokines （IL-33.IL-35.IL -37.IL-38）, which was reviewed in this paper.
作者 张胜佳 田洪清
机构地区 济南大学山东省医学科学院 医学与生命科学学院 山东省皮肤病性病防治研究所
出处 《中国麻风皮肤病杂志》 2015年第5期279-281,共3页 China Journal of Leprosy and Skin Diseases
基金 山东省自然科学基金资助(编号:ZR2013HM076)
关键词 梅毒 细胞免疫 syphilis cellular immunity
分类号 R759.1 [医药卫生—皮肤病学与性病学]
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参考文献23

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  • 8孙澍彬,欧健梅,庄慈妹.CD4^+ CD25^+调节性T细胞与IL-17在梅毒血清固定患者外周血中的表达及意义[J].皮肤性病诊疗学杂志,2012,19(1):19-21. 被引量：9
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二级参考文献11

  • 1赵建斌,龚匡隆,张津萍,钟铭英,尚淑贤,郑波,王千秋.梅毒患者外周血CD4+CD25^(bright)调节性T细胞的检测[J].中华皮肤科杂志,2006,39(5):247-249. 被引量：18
  • 2Podwinska J,Lusiak M,Zaba R,et al.The pattern and level of cytokines secreted by Th1 and Th2 lymphocytes of syphilitic patients correlate to the progression of the disease[J].FEMS Immunol Med Microbiol,2000,28(1):1-14.
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  • 5Taylor AL,Llewelyn MJ.Superantigen-induced proliferation of human CD4+CD25-T cells is followed by a switch to a functional regulatory phenotype[J].J Immunol,2010,185(11):6591-6598.
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  • 10黎志刚,曾仁山.梅毒血清固定患者103例临床分析[J].皮肤性病诊疗学杂志,2010,17(3):204-206. 被引量：19

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中国麻风皮肤病杂志
2015年 第5期

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