2006-2010年中国肿瘤登记地区恶性肿瘤疾病负担研究

Burden of disease due to malignant neoplasms in China,2006-2010

目的了解2006-2010年我国恶性肿瘤发病、死亡情况和疾病负担,为肿瘤防治提供依据。方法收集国家癌症登记中心发布的2006-2010年中国肿瘤登记年报数据,应用发病率、死亡率、潜在减寿年(potential years of life lost,PYLL)和伤残调整生命年(disability adjusted life year,DALY)评价恶性肿瘤疾病负担。结果 2006-2010年我国恶性肿瘤发病率为267.13/10万,男性为299.13/10万,高于女性234.06/10万;城镇地区285.97/10万,高于农村地区250.91/10万。2006-2010年我国恶性肿瘤死亡率为176.32/10万,男性为220.54/10万,高于女性130.60/10万;农村地区为179.25/10万,高于城镇地区172.91/10万。2006-2010年我国恶性肿瘤PYLL为86 567 385人年,男性为52 348 012人年,高于女性34 219 373人年;农村地区59 366 203人年,高于城镇地区36 371 422人年。2006-2010年我国恶性肿瘤导致的DALY为131 436 663个,男性为86 203 604个,高于女性45 233 059个;农村地区78 974 137个,高于城镇地区52 462 526个。结论 2006-2010年我国恶性肿瘤疾病负担较重,农村地区高于城镇,男性高于女性,相关部门应加强肿瘤防治措施,减轻居民肿瘤疾病负担。

OBJECTIVE To investigate the incidence,mortality and disease burden of malignant neoplasms of China from 2006 to 2010,so as to provide reference for cancer prevention and control. METHODS The cancer registry data was based on the published Chinese Cancer Registry Annual Report by National Center for Cancer Registries from 2006 to 2010. The incidence,mortality, potential years of life lost （PYLL） and disability adjusted life year （DALY） were calculat- ed to assess burden of tumour. RESULTS The crude incidence of cancer was 267.13 per 100 000,in which the male and female were 299. 13 per 100 000 and 234. 06 per 100 000 respeetively. The crude mortality of cancer was 176. 32 per 100 000,in which the male and female were 220.54 per 100 000 and 130.60 per 100 000 respectively. The incidence and mortality of cancer in male was steadily higher than that in female. The incidence of cancer in urban areas （285. 97 per 100 000） was higher than that in rural （250.91 per 100 000）. However,the mortality in rural areas （179.25 per 100 000） was higher than that in urban areas （172.91 per 100 000）. PYLL of overall cancer were 86 567 385 （52 348 012 in male and 34 219 373 in female）. The overall DALYs of malignant neoplasms were 131 436 663 （86 203 604 in male and 45 233 059 in female）. The PYLL and DALYs of male were higher than that of female. The PYLL in rural areas （59 366 203） was higher than that in urban （36 371 422）. Similarly,DALYs in rural （78 974 137） were higher than that in urban （52 462 526）. CONCLUSIONS The disease burden of cancer in China was serious. The cancer burden of male, rural district were higher than that of female and urban district. Some preventive and therapeutic measures should be car- ried out so as to reduce the disease burden of cancer by the governmental departments.