摘要
目的分析孟连县钩端螺旋体(钩体)病流行特征,为钩体病预防与控制提供科学依据。方法定期采集不明原因发热患者全血,鼠、蛙、猪肾和水牛中段尿,进行病原体分离培养和显微镜凝集试验,对临床确诊病例和宿主动物血清进行抗体检测和分析。结果孟连县2005 2013年期间,全县6个乡镇共报告钩体病172例,年平均发病率14.88/10万,夏秋季为高发季节,发病率呈现逐年下降的趋势,病例以青壮年和农民为主(81.4%),男性高于女性(1.97∶1)。病例血清分型发现有12个血清群,其中以黄疸出血群为主(37.63%)。多种宿主动物病原学监测总阳性率为2.34%,其中鼠类带菌率最高(3.50%)。结论孟连县近年钩体病疫情整体呈逐年下降的趋势,但其发病率明显高于全国平均水平;当地呈现钩体菌群多样性高和鼠类带菌率较高的地区特征,提示孟连县存在钩体病暴发和流行的可能。
Objective To understand the epidemiological characteristics of leptospirosis in Menglian,Yunan province,and provide evidence for the prevention and control of leptospirosis.Methods The blood samples of patients with unexplained fever,kidney samples of mouse,frogs and pigs and the middle stream urine of buffalos were collected for pathogen isolation / culture and microscopic agglutination test,then the serum antibody detection was conducted for diagnosed patients and host animals.Results During 2005-2013,a total 172 leptospirosis cases were reported in 6townships in Menglian,the average incidence was 14.88 /100 000,The incidence peak was during summer-autumn,the incidence was in decline,Most patients were farmers and young adults（81.4%）,The male to female ratio of the cases was 1.97 ∶ 1.Twelve serogroups of Leptospire were detected,but serogroup icterohemorrhagie was predominant（37.63%）.The overall detection rate was 2.34% in host animal surveillance,but the detection rate was highest in rodents（3.50%）.Conclusion The incidence of leptospirosis was in decline in Menglian,but it was still higher than average national level.Multi serogroups of Leptospire circulated and the rodents＇ carriage of Leptospire was high in Menglian,suggesting the possibility of local leptospirosis outbreak.
出处
《疾病监测》
CAS
2015年第5期399-402,共4页
Disease Surveillance
