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动态调整极化液配伍治疗对急性心肌梗死合并糖尿病患者氧化应激的影响 被引量:4

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摘要 目的:探讨动态调整极化液配伍治疗对急性心肌梗死(AMI)合并糖尿病(DM)患者氧化应激的影响。方法:选择AMI合并DM患者112例,急诊行经皮冠脉介入治疗(PCI)后随机分为动态极化液组(A组)59例,常规极化液组(B组)53例,另设正常对照组(C组)48例。分别在入院第1日及治疗3d后测定血清皮质醇(Cor)、超敏C反应蛋白(hs-CRP)、丙二醛(MDA)、超氧化物歧化酶(SOD)的水平,监测血糖;3d后行24h动态心电图检查,观察心律失常情况。结果:1血清Cor、hs-CRP、MDA水平A组、B组均高于C组,SOD水平低于C组,差异有统计学意义(P<0.05);2A组、B组治疗3d后分别与入院时自身各指标比较差异有统计学意义(P<0.05);A组血清Cor、hs-CRP、MDA较B组降低,差异有统计学意义(P<0.05);3A组血糖更为稳定,心律失常的发生率少于B组。结论:动态调整极化液配伍治疗对AMI合并DM患者有更强的抗氧化应激作用,对稳定血糖、减少PCI后心律失常的发生更有优势。
出处 《陕西医学杂志》 CAS 2015年第6期723-724,734,共3页 Shaanxi Medical Journal
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参考文献10

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