不同手术方式治疗宫颈癌的临床疗效观察

Clinical efficacy of different surgical treatment of cervical cancer

目的探讨不同手术方式治疗宫颈癌的临床疗效。方法选取广州市南沙中心医院2010年6月至2011年6月收治的90例宫颈癌患者的临床资料,依据采用的不同手术方式分为A、B组,每组各45例。A组患者采取腹腔镜手术,B组患者采取开腹手术,观察两组的临床治疗效果。结果 A组手术时间[(145.7±12.7)min]、术中出血量[(225.3±34.6)m L]、肛门排气时间[(32.5±6.7)h]、下床活动时间[(1.7±0.3)d]、住院时间[(16.9±3.5)d]、术后并发症发生率(6.7%)均少于B组[分别为(213.6±21.8)min、(342.6±51.6)m L、(58.4±9.3)h、(2.7±0.4)d、(20.5±4.1)d、20.0%](P均<0.05)。A、B组复发率分别为4.4%、6.7%,差异无统计学意义(P>0.05)。结论腹腔镜手术治疗宫颈癌创伤小、手术时间短、术中出血量少,降低术后并发症,能较好的促进术后恢复。

Objective To investigate the clinical efficacy of different operation methods in treatment of cervical cancer. Methods Clinical data of 90 cases with cervical cancer in Guangzhou Nansha Center Hospital from Jun 2010 to Jun 2011were selected.All cases were divided into group A and group B according to the different operation methods with 45 cases in each group. The patients in group A were under the treatment of laparoscopic operation, while patients in group B underwent laparotomy, clinical therapeutic effect of two groups were observed.Results The operation time[（145.7 ±12.7） min], intraoperative bleeding amount [（225.3 ±34.6） mL], anal exhaust time[（32.5 ±6.7） h], ambulation time[（1.7 ±0.3） d],hospitalization time[（16.9 ±3.5） d] and complications rate（6.7 %） in group A were less than that in Group B[（213.6 ±21.8）min, （342.6 ±51.6） mL, （58.4 ±9.3） h, （2.7 ±0.4） d, （20.5 ±4.1） d, 20.0 %respectively]（P 〈0.05）.The difference in recurrence rate between group A （4.4 %） and group B （6.7%） had no statistical significance （P〉0.05）.Conclusion The application of laparoscopic has advantages of little trauma, short operation time, less blood loss, reducing the postoperative complications, which can promote recovery after operation.