摘要
研究证实中性粒细胞胞外诱捕网参与病原微生物引起的先天免疫应答反应。最近研究发现在非感染性炎性疾病中也存在中性粒细胞胞外诱捕网。中性粒细胞胞外诱捕网形成增多或者降解异常都会影响急、慢性炎性疾病的病理过程。本篇文章介绍了中性粒细胞胞外诱捕网的形成及作用,着重介绍在非感染性炎性疾病的意义。
Researches have showed that neutrophil extracellular traps （NETs） involve in antimicrobial innate immunity. Meanwhile, NETs have recently been discovered in non-infections diseases. Aberrantly enhanced NETs formation or decreased NETs degradation will affect disease outcome in acute or chronic inflammatory disorders. This review summarizes how NETs are made and their function in diseases, especially in non-infectious inflammatory diseases.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2015年第6期537-540,共4页
Immunological Journal
关键词
中性粒细胞胞外诱捕网
病原微生物
非感染性炎性疾病
Neutrophil extracellular traps
Pathogenic microorganisms
Non-infectious inflammatory diseases
