某院血液病科2012～2013年细菌耐药性分析

Analysis of Antibiotic Resistance in Hematological Department of one Hospital from 2012 to 2013

目的：调查某院血液病科2012~2013年分离细菌分布及其对抗菌药的耐药状况,为临床合理使用抗菌药提供依据。方法：对该科2012~2013年住院患者送检标本中分离得到的致病菌进行对比分析。结果：排在前三位的分别为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌,大肠埃希菌和肺炎克雷白菌产ESBL比例分别为66.7%和32.1%,大肠埃希菌和肺炎克雷伯菌对替加环素的耐药率分别为5.8%和5.7%,凝固酶阴性葡萄球菌和金黄色葡萄球菌对苯唑西林耐药率分别为91.3%和31.6%,肺炎链球菌对青霉素的耐药率为5.0%。结论：掌握该科室的细菌分布及耐药变迁,对促进抗菌药的合理选用,减少细菌耐药性的产生具有重要意义。

Objective：To advise rational using of antibiotic drugs by according to the outcome of investigating the pathogen distribution and antibiotic resistance of inpatients in hematological department from 2012 to 2013. Methods： To analyze the pathogenic bacteria separating from the samples of patents from 2012 to 2013. Results：The main strains were Escherichia coli （eco） , Klebsiella pneumonia （kpn） and Pseudornonas aeruginosa （pae） in hematological department from 2012 to 2013, the ESBL of eco and kpn was about 66.7% and 32.1%. The antibiotic resistance of eco and kpn for tigecy- cline was 5.8 % and 5.7% , respectively. The antibiotic resistance of Coagulase negative Staphylococcus and Staphylococcus aureus for oxacillin was 91.3% and 31.6%. The antibiotic resistance of Streptococcus Prteumoniae for penicillin was 5.8%. Conclusion：It is important to know the bacteria distribution and antibiotic resistance tot promoting the rationality of using antibiotic drugs and reducing antibiotic resistance.