盐酸戊乙奎醚治疗急性有机磷农药中毒的临床研究

Clinical research of penehyclidine hydrochloride in the treatment of acute organophosphorus pesticide poisoning

目的探讨盐酸戊乙奎醚治疗急性有机磷农药中毒的临床疗效。方法 60例急性有机磷农药中毒患者,随机分为对照组和研究组,各30例。对照组使用阿托品治疗,研究组使用盐酸戊乙奎醚治疗,对比两组患者的治疗结果。结果研究组患者的治疗结果显著优于对照组,差异有统计学意义(P<0.05)。结论应用盐酸戊乙奎醚治疗急性有机磷农药中毒患者疗效显著,临床上应当进一步推广应用。

Objective To investigate the clinical effect of penehyclidine hydrochloride in the treatment of acute organophosphorus pesticide poisoning. Methods A total of 60 acute organophosphorus pesticide poisoning patients were randomly divided into control group and research group, with 30 cases in each group. The control group received atropine for treatment, and the research group received penehyclidine hydrochloride. Curative effects of the two groups were compared. Results The research group had much better curative effect than the control group, and their difference had statistical significance （/9〈0.05）. Conclusion Implement of penehyclidine hydrochloride provides significant effect in the treatment of acute organophosphorus pesticide poisoning. This method is worth further clinical promotion and application.