期刊文献+

黄体酮阴道凝胶联合吲哚美辛片治疗先兆早产的效果分析 被引量:3

下载PDF
导出
摘要 目的探讨黄体酮阴道凝胶联合吲哚美辛片治疗先兆早产的临床效果。方法 100例诊断为先兆早产的单胎初产孕妇,随机分成观察组和对照组,每组50例。对照组采用吲哚美辛片治疗,观察组使用吲哚美辛片和黄体酮阴道凝胶治疗。记录延长妊娠时间、≥32周分娩率、新生儿窒息发生情况及新生儿体重。结果观察组延长妊娠时间、≥32周分娩率、新生儿体重疗效均明显优于对照组(P<0.05),吲哚美辛使用时间明显少于对照组(P<0.05)。结论黄体酮阴道凝胶联合吲哚美辛片治疗先兆早产可延长孕周,改善新生儿预后,防止吲哚美辛片多次使用导致胎儿动脉导管早闭的胎儿畸形。
出处 《中国现代药物应用》 2015年第13期143-145,共3页 Chinese Journal of Modern Drug Application
  • 相关文献

参考文献10

  • 1乐杰.妇产科学.第7版.北京:人民卫生出版社,2009:105-112.
  • 2胡娅莉,周乙华,杨慧霞.重视妊娠合并症及并发症的防治[J].中华妇产科杂志,2010,45(1):5-7. 被引量:15
  • 3Barden TP, Peter JB, Merkatz IR. Ritodrine hudrehloride: a beta mimetic agent for use in Preterm labor .I Pharrmacology, clinical history , adnimistration, side effects, anti safety. Obstet Gynecol, 1980, 56(1):1-6.
  • 4Yajun Y, Nakayama T. Effectiveness and safety of ritodrine hydrochloride for the treatment of preterm labour: a systematic review. Pharmacoepidenfiol Drug Saf, 2006, 15(11):813-822.
  • 5DeFranco EA, O'Brien JM, Adair CD, et al. Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo- controlle trial. Ultrasound Obstet Gynecol, 2007, 30(5):697-705.
  • 6Hassan SS, Romero R, Vidyadhari D, et al. Vaginalprogesterone reduces the rate of pl~term birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, plaeebo-conlrolled trial. Ultrasound Obstet Gyneeol, 2011, 38(1): 18-31.
  • 7Cetingoz E , Cam C , Sakalh M, et al. Progesterone effects on preterm birth in high-risk pregnancies: a randomized placebo- controlled trial. Arch Gynecol Ohstet, 2011,283(3):423-429.
  • 8杨慧霞.胎肺成熟机制及促胎肺成熟的治疗[J].中国实用妇科与产科杂志,2003,19(2):72-73. 被引量:18
  • 9Meis PJ , Klebanoff M, Thorn E, et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxy progesterone eaproate. NEngl J Med, 2003, 58(11): 704-706.
  • 10da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterrn birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gyneeol, 2003, 188(2):419-424.

二级参考文献21

  • 1刘崇柏,苏崇鳌.对乙型肝炎免疫球蛋白阻断母婴围产期传播的浅见[J].中国计划免疫,2006,12(2):148-150. 被引量:14
  • 2Dodd JM, Flenady VJ, Cinotta R, et al. Progesterone for prevention of preterm birth. Obstet Gynecol, 2008, 112 : 127-134.
  • 3Norman JE, Mackenzie F, Owen P, et al. Progesterone for the prevention of preterm birth in twin pregnancy ( STOPPIT ) : a randomised, double-blind, placebo-controlled study and meta- analysis. Lancet, 2009,373:2034-2040.
  • 4Robert L, Goldenberg MD, William W,et al. Alabama preterm birth study: umbilical cord blood ureaplasma urealyticum and mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol, 2008, 198:43 e1-e5.
  • 5King J, Flenady V. Antibiotics for inhibiting preterm labor with intact membranes. Cochrane Database Syst Rev, 2002, CD000246.
  • 6Kenyon S, Boulvain M, Neilson J. Antibiotics for preterm rupture of membranes. Cochrane Database Syst Rev, 2003, CD 001058.
  • 7Kenyon S, Pike K, Jones DR, et al. Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7 year follow-up of ORACLE I trial. Lancet, 2008, 372: 1310-1318.
  • 8Drakeley A, Roberts D, Alfirevic Z. Cervical stich (cerclage) for preventing pregnancy loss in women. Cochrane Database Syst Rev, 2003, CD003253.
  • 9Bachmann L, Coomarasamy A, Honest H, et al. Elective cervical cerclage for prevention of preterm birth. Acta Obstet Gynecol Scand, 2003, 82:398-404.
  • 10Poland GA, Jacobson RM. Clinical practice: prevention of hepatitis B with the hepatitis B vaccine. N Engl J Med, 2004,351: 2832-2838.

共引文献67

同被引文献21

引证文献3

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部