期刊文献+

甲状腺功能正常孕早期妇女TPO抗体阳性与产后甲状腺炎关系的研究 被引量:4

下载PDF
导出
摘要 目的通过对甲状腺功能正常的孕早期妇女甲状腺过氧化物酶抗体(TPOAb)的测定,了解其与孕妇产后甲状腺炎的关系。方法本研究选取甲状腺功能正常的孕早期妇女作为研究对象,监测并比较TPOAb高滴度组和低滴度组孕妇在分娩后1年内甲状腺功能的变化;比较两组孕妇产后甲状腺炎发生率的差异。结果本文TPOAb高滴度组42例患者中发生产后甲状腺炎患者7例,患病率为16.67%;TPOAb低滴度组86例患者中发生产后甲状腺炎患者12例,患病率为13.95%;两组差异无统计学意义(>0.05)。结论 TPOAb高滴度组孕妇产后甲状腺炎的发生率与低滴度组差异无统计学意义,不管抗体是高滴度还是低滴度,都要予以足够的重视。
出处 《现代实用医学》 2015年第5期650-651,共2页 Modern Practical Medicine
基金 宁波市科技局社会发展项目(2014C50075)
  • 相关文献

参考文献6

二级参考文献46

  • 1高金瑜,王谢桐.甲状腺自身抗体与复发性流产关系的初步探讨[J].中国实用妇科与产科杂志,2006,22(12):915-917. 被引量:22
  • 2Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin End~rinol Metab, 2007,92 (8 Suppl) :S1-47.
  • 3Stagnaro-Green A, Aba|ovich M, Alexander E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid, 2011,21 : 1081-1125.
  • 4Yah YQ, Dong ZL, Dong L, et al. Trimester- and method-specific reference intervals for thyroid tests in pregnant Chinese women: methodology, euthyroid definition, and iodine status can influence the setting of reference intervals. Clin Endocrinol ( Oxf), 2011,74 : 262- 269.
  • 5Baloch Z, Carayon P, Coute-Devoix B, eta|. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid, 2003, 13: 3- 126.
  • 6Guan H, Shan Z, Teng X, et al. Influence of iodine on the reference interval of TSH and the optimal interval of TSH : results of a follow-up study in areas with different iodine intakes. Clin Endocrinol ( Oxf), 2008,69 : 136-141.
  • 7Hollowell JG, Staehling NW, Flanders WD, et al. Serum TSH, T(4) , and thyroid antibodies in the United States population ( 1988 to 1994) : National Health and Nutrition Examination Smwey ( NHANES III). J Clin Endocrinol Metab, 2002,87:489-499.
  • 8Arnaud-Lopez L, Usala G, Ceresini G, et al. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Am J Hum Genet, 2008,82 : 1270-1280.
  • 9Glinoer D, Spencer CA. Serum TSH determinations in pregnancy: how, when, and why? Nat Rev Endocrinol, 2010,6:526-529.
  • 10Lazarus JH, Bestwick JP, Channon S, et al. Antenatal thyroid screening and childhood cognitive function. N Engl J Med, 2012,366 : 493-501.

共引文献170

同被引文献24

引证文献4

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部