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前哨淋巴结转移阳性对非前哨淋巴结转移的预测效能研究 被引量:2

Effectiveness of predicting non-sentinel lymph node metastasis by sentinel lymph node metastasis
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摘要 目的探讨前哨淋巴结转移阳性对非前哨淋巴结转移的预测效能。方法选择前哨淋巴结活检的乳腺癌患者共157例,检测前哨淋巴结转移情况,并分析前哨淋巴结转移阳性对非前哨淋巴结转移的预测效能。结果 157例患者共检出前哨淋巴结341枚,共发现转移的前哨淋巴结87枚。共清除非前哨淋巴结2 281枚,发现转移共301枚。非前哨淋巴结假阴性率为9.76%(8/82),其敏感度为95.12%(78/82),特异性为87.23%(81/94),准确度为87.26%(137/157)。结论前哨淋巴结转移阳性对非前哨淋巴结转移具有较好的预测效能。 Objective To investigate the effectiveness of predicting non-sentinel lymph node metastasis by sentinel lymph node metasta-sis. Methods A total of 157 cases of sentinel lymph node biopsy were collected and the detection of sentinel lymph node metastasis was taken. Analysis of sentinel lymph node metastasis for non-sentinellymph node metastasis prediction was undertaken. Results 341 sentinel lymph node were found in the 157 patients,87 were found in the sentinel lymph node metastasis. A total of 2281 non-sentinel lymph nodes were cleared,and a total of 301 were found transferred. False negative rate of non-sentinel lymph node was 9. 76%(8/82),with the sensitivity of 95. 12%(78/82),a specificity of 87. 23%(81/94)and the accuracy rate was 87. 26%(137/157). Conclusion The sentinel lymph node metastasis has bet-ter predictive performance to non sentinel lymph nodemetastasis.
出处 《临床和实验医学杂志》 2015年第11期881-883,共3页 Journal of Clinical and Experimental Medicine
关键词 前哨淋巴结 转移 非前哨淋巴结 预测 Sentinel lymph node Metastasis Non-sentinel lymph nodes Predicting
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参考文献11

  • 1刘瑾琨,于志强,伍建春,佟建蒙,王先明.乳腺癌前哨淋巴结活检指导腋窝淋巴结清扫[J].临床和实验医学杂志,2010,9(9):677-678. 被引量:2
  • 2Biolehini F, Vieentini M, Di Feliee E, et al. Axillary nodal metastases in Italian early breast cancer patients with positive sentinel lymph node: can axillary node dissection be avoided by using predictive nomoga'arns [J] ? Tumori, 2015 Apr 2. doi: I0. 5301/tj. 5000281.
  • 3Langer I, GuUer U, Berdaz G, et at. Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN and completion axillary lymph node dis- section after breast eancer surgery: a prespeetive Swiss multieenter study on 659 patients[ J]. Ann Surg, 2007,245(3) :452 -461.
  • 4Kootstra JJ, Hoekstra - Weebers JE, Rietman JS, et at. A longitudinal comparison of ann morbidity in stage I - II breast cancer patients treated with sentinel lymph node biopsy, sentinel lymph node biopsy followed by completion lymph node dissection, or axillary lymph node dissection [J]. Ann Surg Oncol, 2010,17(9) :2384 -2394.
  • 5Ahmed M, Anninga B, Goyal S, et al. Magaaetic sentinel node and oc- cult lesion localization in breast cancer (MagSNOLL Trial) [11. Br J Surg, 2015,102(6) :646 -652.
  • 6Gherghe M, Bordea C, Blidaru A. Sentinel lymph node biopsy (SLNB) vs. axillary lymph node dissection (ALND) in the current surgical treat- ment of early stage breast cancer[ J]. J Med Life, 2015,8 (2) :176 - 180.
  • 7Kim T, Giuliano AE, Lyman GH. Lymphatic mapping and sentinel lymph node biopsy in early - stage breast carcinoma: a metaanalysis [J]. Cancer, 2006,106(1):4 -16.
  • 8Van la Parra RF, Peer PG, Ernst MF, et al. Meta - analysis of predic- tive factors for non - sentinel lymph node metastases in breast cancer pa- tients with a positive SLN [ J ]. Eur J Surg O ncol, 2011,37 (4) :290 - 299.
  • 9Tanaka S, Sato N, Fujioka H, et al. Validation of online calculators to predict the non - sentinel lymph node status in sentinel lymph node - positive breast cancer patients [ J ]. Surg Today, 2013,43 ( 2 ) : 163 - 170.
  • 10Hessman CJ, Nalk AM, Keamey NM, et al. Comparative validation of online nomograms for predicting nonsentinel lymph node status in senti- nel lymph node - positive breast cancer[ J ]. Arch Surg, 2011,146 (9) : 1035 - 1040.

二级参考文献20

  • 1Cody HS 3rd,Fey J,Akhurst T,et al.Complementrarity of blue dye and isotope in sentinel node localization for breast cancer:univariate and multivariate analysis of 966 procedures[J].Ann Surg Oncol,2001,8(1):13-19.
  • 2Noguchi M.Sentinel lymph node biopsy and breast cancer[J].Br J Surg,2002,89(1):21-34.
  • 3Turner RR,Ollila DW,Krasne DL,et al.Histopathologic validation of the sentinel lymph node hypothesis for breast carcinoma[J].Ann Surg,1997,226(3):271-276.
  • 4Ouellette RJ,Richard D,Maicas E.RT-PCR for mammaglobin genes,MGB1 and MGB2,identifies breast cancermicrometastases in sentinel lymph nodes[J].Am J Clin Pathol,2004,121(5):637-643.
  • 5Eldweny H, Alkhaldy K, Alsaleh N, et al. Predictors of non-senti- nel lymph node metastasis in breast cancer patients with positive sentinel lymph node[J].J Egypt Nail Canc Inst, 2012, 24(1):23-30.
  • 6Meretoja TJ,Leidenius MH, Heikkila PS, et al. International multi- center tool to predict the risk of nonsentinel node metastases in breast cancer[J].J Natl Cancer Inst, 2012, 104(24):1888-1896.
  • 7Van Zee KJ, Manasseh DM, BevilacquaJL, et al. A nomogram for predicting the likelihood of additional nodal metastases in breast cancer patients with a positive sentinel node biopsy[J]. Ann Surg Oncol, 2003, 10(10):1140-1151.
  • 8Kohrt HE, Olshen RA, Bermas HR, et al. New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients[J]. BMC Cancer, 2008, 4 (8) :66.
  • 9Hessman CJ, Naik AM, Kearney NM, et al. Comparative Valida- tion of Online Nomograms for Predicting Nonsentinel Lymph Node Status in Sentinel Lymph Node - Positive Breast Cancer[J]. Arch Surg, 2011, 146(9):1035-1040.
  • 10Scomersi S, Torelli L, Zanconati F, et al. Evaluation of a breast can- cer nomogram for predictiong the likelihood of additional nodal me- tastases in patients with a positive node biopsy[J]. Ann Ital Chit, 2012, 83 (6) :461--468.

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