摘要
Objective To explore quality of life(QOL) and its influencing factors in patients with lung cancer.Methods A QOL questionnaire(European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire-Core 30 [QLQ-C30] Chinese version) was used with 138 patients with lung cancer participating in the study. A statistical description of the general characteristics of the patients with lung cancer was performed. The patients' QLQ-C30 scores were compared with the reference value for each dimension. To analyze the influence of QOL in different genders, age groups, and cancer stages, ttests and rank sum tests were used to compare the differences in QOL using a 5% significance level. Results The QLQ-C30 function scores in PF(physical functioning), EF(emotional functioning), SF(social functioning), and GH(global functioning), and symptom scales in NV(nausea and vomiting), DY(dyspnea), SL(insomnia), and FI(financial difficulties) were significantly different(P < 0.05) in comparison to the reference values. Female patients were worse than males(P < 0.05) in EF, NV, and DI(diarrhea). The later the stage of lung cancer, the worse the quality of life became; the functional scales in RF(role functioning), EF, CF, SF, and GH, and symptom scales in PA(pain), AP(appetite), and SL differences were statistically significant(P < 0.05). Conclusion This study aids understanding of the status of the quality of life of Chinese patients with cancer and might be useful for clinical work, theory research, and health policymakers.
Objective To explore quality of life （QOL） and its influencing factors in patients with lung cancer. Methods A QOL questionnaire （European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire-Core 30 [QLQ-C30] Chinese version） was used with 138 patients with lung cancer participating in the study. A statistical description of the general characteristics of the patients with lung cancer was performed. The patients＇ QLQ-C30 scores were compared with the reference value for each dimension. To analyze the influence of QOL in different genders, age groups, and cancer stages, t-tests and rank sum tests were used to compare the differences in QOL using a 5% significance level. Results The QLQ-C30 function scores in PF （physical functioning）, EF （emotional functioning）, SF （social functioning）, and GH （global functioning）, and symptom scales in NV （nausea and vomiting）, DY （dyspnea）, SL （insomnia）, and FI （financial difficulties） were significantly different （P 〈 0.05） in comparison to the reference values. Female patients were worse than males （P 〈 0.05） in EF, NV, and DI （diarrhea）. The later the stage of lung cancer, the worse the quality of life became; the functional scales in RF （role functioning）, EF, CF, SF, and GH, and symptom scales in PA （pain）, AP （appetite）, and SL differences were statistically significant （P 〈 0.05）. Conclusion This study aids understanding of the status of the quality of life of Chinese patients with cancer and might be useful for clinical work, theory research, and health policymakers.
基金
Supported by the Natural Science Foundation of Hubei Province(No.2013 CFB138)
Hubei Province Health and Family Planning Scientific Research Project(No.WJ2015Q009)
关键词
肿瘤
诊断
临床
化疗
疗效
quality of life
lung cancer
EORTC QLQ-C30
influential factors
