血乳酸水平在儿童感染性休克治疗中的临床意义

Clinical Significance of Blood Lactic Acid Level in Treating Children with Septic Shock

目的探讨儿童感染性休克治疗中监测血乳酸水平对临床效果的影响。方法随机入选的60例感染性休克患儿分为观察组和对照组,每组30例。两组患儿均进行感染性休克常规治疗和中心静脉压监测补液,观察组另外添加血乳酸测定,观察两组患者治疗后的生理指标变化和预后情况。结果观察组从第2天开始,白细胞计数、中性粒细胞百分比、乳酸水平明显低于对照组、混合静脉血氧饱显著高于对照组,观察组28 d死亡率(16.67%)显著低于对照组(43.33%),差异比较均具有统计学意义(P<0.05)。结论血乳酸监测指导性治疗儿童感染性休克,可有效的改善患儿的生理指标,降低死亡率,对感染性休克患儿病情和预后的评估具有重要意义。

Objective To discuss the clinical value of monitoring blood lactic acid level in children with septic shock. Methods 60 children with septic shock were randomly selected and divided into the observation group and the control group, with 30 cases in each group respectively. Patients in both groups were given routine treatment and central venous pressure monitoring rehydration, while patients in the observation group received the additional treatment of blood lactic acid determination. Changes of physiological indexes and prognosis situation of the two groups were observed after treatment. Results From the second day on, leukocyte count, neutro-phil percentage and lactic acid levels of the observation group was significantly lower than that of the control group, mixed venous blood oxygen full was significantly higher than that of the control group, and 28-day mortality of the observation group (16. 67%) was sig-nificantly lower than that of the control group (43. 33%), with statistically significant difference (P<0. 05). Conclusion Monitoring blood lactic acid level in treating children with septic shock can effectively improve children ’ s physiological indicators and reduce mortality, which proves to be of significance to the severity assessment and prognosis of patients with septic shock.