早复极与早复极综合征

Early Repolarization and Early Repolarization Syndrome

早复极长期以来被认为是一种正常的心电图变异,近年观察到部分早复极患者可发生严重室性心律失常和心源性猝死。2013年由HRS/EHRA/APHRS/PACE/ACFF/AHA联合发布了"遗传性心律失常综合征专家共识"。将早复极综合征正式列入遗传性心律失常综合征。本文结合"专家共识"和近年文献对早复极及早复极综合征发病机制、临床心电图表现、诊断、鉴别诊断及治疗等做一新的简述。

Early repolarization （ER） was ever known as a normal electrocardiogram variation. In recent years, it had been found that some patients with ER were attacked by malignant ventricular arrhythmias and sudden cardiac death. Expert Consensus on the Diagnosis and Management of Patients with Inherited Primary Arrhythmia Syndromes was jointly issued by HRS, EHRA, APHRS, PACE, ACFF and AHA in 2013, in which ERS was taken into account in Inherited Primary Arrhythmia Syndromes. On the basis of the ＂Expert Consensus＂ and the recent literature, this paper is to focus on pathogenesis of ER and ERS, the features of clinical ECG, diagnosis, differential diagnosis and treatment.