亚硫酸氢钠甲萘醌注射液静脉滴注给药的合理性与安全性分析

Rationality and security on the intravenous drip of menadione sodium bisulfite injections

目的通过对住院病历的医嘱点评,对我院亚硫酸氢钠甲萘醌注射液的用药现状进行统计分析,并提出合理化的改进措施。方法选取2014年1~6月医院亚硫酸氢钠甲萘醌注射液使用部门进行统计,取使用频率较高的科室排序前3名的数据进行统计分析。结果临床采用亚硫酸氢钠甲萘醌注射液静脉滴注给药存在超剂量和给药途径不适宜等超说明书使用现象,静脉滴注给药中也未采取任何避光措施,加大了亚硫酸氢钠甲萘醌注射液临床使用的风险。结论医院药事管理与药物治疗学委员会和医务部门采取措施,停止亚硫酸氢钠甲萘醌注射液临床静脉滴注给药用法,严格按照药品说明书规定的适应证和用法用量使用,加强用药监护,降低严重药品不良反应的发生,保障用药安全。

Objective Through the prescribed reviews of medical records,the current situation of medication in our hospital about menadione sodium bisulfite injection was analyzed statistically,and proposed the improvement measures for the rationalization. Methods From January to June 2014,the department used of menadione sodium bisulfite injection was selected for statistics. The data of ranking the top 3 departments with higher use frequency were analyzed statistically. Results In the course of using menadione sodium bisulfite injections,there is a phenomenon of the use of ultra manual such as super dose and inappropriate administration route. And the intravenous infusion of the drug did not take any measures to avoid light.This increased the risk of sodium bisulfite menadione injection in clinical use. Conclusion The hospital pharmacy,therapeutics committee and medical departments should take measures to stop clinical intravenous injection of menadione sodium bisulfite and make a prescription strictly according to the indications and dosage of the drug instruction manual,strengthen medication monitoring,in order to reduce the occurrence of serious adverse drug reactions and protect public safety.