加味温胆汤对痰浊型高血压病患者相关危险因子的影响

Effects of Jiawei Wendan decoction on the related risk factors in patients with turbid phlegm type hypertension

目的:研究加味温胆汤对痰浊型高血压病患者的相关危险因子的影响。方法:采用前瞻性随机分组的方法,将入选病例按就诊顺序分为治疗组和对照组,每组各30例,治疗组在基础治疗上加用加味温胆汤,4周为1个疗程,持续3个疗程。观察两组患者治疗前后的中医症状、体重指数(BMI)、腰围、血压水平、空腹血糖(GLU)、餐后2h血糖、总胆固醇(CHOL)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸(UA)、血常规、二便常规、肝肾功能情况。结果:经治疗后两组的糖脂尿酸代谢指标及血压水平均有所下降,且治疗组糖脂尿酸代谢指标及血压水平的下降程度均优于对照组,差异具有统计学意义(P<0.05)。结论:西药加用加味温胆汤对痰浊型高血压病患者的临床症状、糖脂尿酸指标及血压水平的改善情况明显优于单纯使用西药。

Objective： To study the effects of Jiawei Wendan tonga taste on the related risk factors in patients with turbid phlegm type hypertension. Methods： Using a prospective randomized method, the selected patients were randomly divided into the treatment group and control group with 30 cases in each. The treatment group was treated by Jiawei Wendan tonga taste, 4 weeks as a course, 3 courses. Observed in the two groups before and after treatment of TCM symptoms, body mass index （BMI）, waist circumference, blood pressure, fasting blood glucose （GLU）, 2 hour postprandial blood glucose, total cholesterol （CHOL）, triglyceride （TG）, high density lipoprotein cholesterol （HDL-C）, low density lipoprotein cholesterol （LDL-C）, uric acid （UA）, blood routine test, two routine, liver and kidney function. Results： After treatment, two groups of lipid and uric acid metabolism index and blood pressure decreased. The treatment group, compared with the control group, decreased lipidmetabolism of uric acid index and blood pressure are better than the control group. The difference was statistically significant （P〈O.05）. Conclusion： Western medicine with Jiawei Wendan tonga taste, improved the situation of patients with turbid phlegm type hypertension clinical symptoms, glucose and uric acid index and blood pressure level, is obviously superior to the single use of western medicine.