五神汤加减治疗慢性骨髓炎的疗效分析

An efficacy analysis of treating chronic osteomyelitis with the Wushen decoction

目的：探讨五神汤加减治疗慢性骨髓炎的效果。方法：选择2009年6月-2013年4月我院收治的慢性骨髓炎患者70例,分为观察组和对照组,每组各35例,对照组给予常规抗感染治疗或手术治疗,观察组在治疗组的基础上给予内服五神汤。根据《临床疾病诊断依据治愈好转标准》评定治疗效果,同时检测治疗前后的白细胞计数、血沉和C-反应蛋白。并对随访时的复发人数进行统计。结果：观察组的总有效率为91.43%;对照组的总有效率为85.71%。两组比较,差异有统计学意义（P〈0.05）。两组治疗前和治疗后在白细胞计数、血沉和C-反应蛋白水平方面的比较,观察组在白细胞计数和血沉方面的水平变化均低于对照组,两者比较,其差异有统计学意义（P〈0.05）,但在C-反应蛋白方面,两组治疗后无明显变化（P〉0.05）。两组分别随访6~10个月,观察组的复发率为18.18%,对照组的复发率为36.67%,两者比较,差异有统计学意义（P〈0.05）。结论：五神汤加减治疗慢性骨髓炎不论在总有效率、白细胞计数、血沉方面,还是在疾病复发方面均优于单纯采用抗生素或手术治疗,值得在临床上推广应用。

Objective： To discuss effects of the Wushen decoction on chronic osteomyelitis. Methods： 70 cases were divided into the observed and control group, 35 for each. The control group was given conventional anti-infection or surgery. The observed group was given the Wushen decoction more. Results： The total efficiency was 91.43% in the observed＇ group, and 85.71% in the control group. By comparing two groups, the difference was statistical significant （P〈0.05）. After the treatment, white blood cell counts and erythrocyte sedimentation rate were lower in the observed group. The difference was statistical significant （P〈0.05）. There was no obvious changes in C-reaction criteria in both groups before and after treatment （P〈0.05）. Both groups respectively were followed up for 6 tol0 months, the recurrence rate was 18.18% in the observed group and 36.67% in the control group. The difference was not statistically significant （P〈0.05） Conclusion： Treating chronic osteomyelitis with the Wushen decoction was better than conventional anti-infection or surgery, is worthy of promotion.