摘要
This review describes work presented in the 2014 inaugural Tsinghua University Press-Springer Nano Research Award lecture, as well as current and future opportunities for nanoscience research at the interface with brain science. First, we briefly summarize some of the considerations and the research journey that has led to our focus on bottom-up nanoscale science and technology. Second, we recapitulate the motivation for and our seminal contributions to nanowire- based nanoscience and technology, including the rational design and synthesis of increasingly complex nanowire structures, and the corresponding broad range of ＂applications＂ enabled by the capability to control structure, com- position and size from the atomic level upwards. Third, we describe in more detail nanowire-based electronic devices as revolutionary tools for brain science, including （i） motivation for nanoelectronics in brain science, （ii） demonstration of nanowire nanoelectronic arrays for high-spatial/high-temporal resolution extracellular recording, （iii） the development of fundamentally-new intracellular nanoelectronic devices that approach the sizes of single ion channels, （iv） the introduction and demonstration of a new paradigm for innervating cell networks with addressable nanoelectronic arrays in three-dimensions. Last, we conclude with a brief discussion of the exciting and potentially transformative advances expected to come from work at the nanoelectronics-brain interface.
这评论描述在大脑科学的接口为 nanoscience 研究在 2014 就职清华大学出版社春天 Nano 研究奖品讲课，以及现在和将来的机会介绍的工作。首先，我们简短总结一些考虑和在自底向上的 nanoscale 科技上导致了我们的焦点的研究旅行。第二，我们概括动机为，我们对基于 nanowire 的 nanoscience 和技术的精液的贡献，和相应女人能力启用向上从原子水平控制结构，作文和尺寸的应用变化，包括逐渐地复杂的 nanowire 结构的合理设计和合成。第三，我们为大脑科学把更详细地 基于nanowire 的电子设备描述为革命工具包括在大脑科学的 nanoelectronics 的(i)动机，( ii ) nanowire nanoelectronic 的示范为 high-spatial/high-temporal 穿分辨率细胞外的记录，( iii )接近单个离子隧道的尺寸的根本上新的细胞内部的 nanoelectronic 设备的开发，( iv )为刺激房间的一个新范例的介绍和示范联网 w 最后，我们与期望在 nanoelectronics 大脑接口来自工作的令人激动、潜在地变化的进展的简短讨论得出结论。
