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Wnt信号通路与头颈鳞状细胞癌

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摘要 Wnt信号通路是一条高度保守的信号转导通路,参与了多种胚胎的发育过程.其通过调节细胞的增殖、分化、凋亡、黏附、迁移和极性等,在机体发育及各种生理过程中起着重要作用.人们发现在多种人类癌症包括头颈鳞状细胞癌中此通路处于异常活化状态.因此,Wnt通路分子生物学机制与基因表达调节规律的研究对头颈鳞状细胞癌具有重要意义.现就Wnt信号通路与头颈鳞状细胞癌的相关研究近况做一综述.
作者 黄鑫 于锋
出处 《国际耳鼻咽喉头颈外科杂志》 2015年第2期96-99,共4页 International Journal of Otolaryngology-Head and Neck Surgery
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