1Mammen, M.; Choi, S. K.; Whitesides, G. M. Polyvalent interactions in biological systems: Implications for design and use of multivalent ligands and inhibitors. Angew. Chem. lnt. Ed. 1998, 37, 2754-2794.
2Saphire, E. O.; Stanfield, R. L.; Crispin, M. D. M.; Parren, P.; Rudd, P. M.; Dwek, R. A.; Burton, D. R.; Wilson, I. A. Contrasting IgG structures reveal extreme asymmetry and flexibility. ,I. Mol. Biol. 2002, 319, 9-18.
3Sandin, S.; 0fverstedt, L. G.; Wikstrrm, A. C.; Wrange, 0.; Skoglund, U. Structure and flexibility of individual immunog- lobulin G molecules in solution. Structure 2004, 12, 409-415.
4Szenczi, A.; Kardos, J.; Medgyesi, G. A.; Zavodszky, P. The effect of solvent environment on the conformation and stability of human polyclonal IgG in solution. Biologicals 2006, 34, 5 14.
5Ando, T.; Kodera, N.; Takai, E.; Maruyama, D.; Saito, K.; Toda, A. A high-speed atomic force microscope for studying biological macromolecules. P. Natl. Acad. Sci. USA 2001, 98, 12468-12472.
6Engel, A.; Muller, D. J. Observing single biomolecules at work with the atomic force microscope. Nat. Struct. Biol. 2000, 7, 715-718.
7Higgins, M. J.; Polcik, M.; Fukuma, T.; Sader, J. E.; Nakayama, Y.; Jarvis, S. P. Structured water layers adjacent to biological membranes. Biophys. J. 2006, 91, 2532-2542.
8Muller, D. J.; Sapra, K. T.; Scheuring, S.; Kedrov, A.; Frederix, P. L.; Fotiadis, D.; Engel, A. Single-molecule studies of membrane proteins. Curr. Opin. Struc. BioL 2006, 16, 489-495.
9Picas, L.; Rico, F.; Scheuring, S. Direct measurement of the mechanical properties of lipid phases in supported bilayers. Biophys. J. 2012, 102, L1-L3.
10Rief, M.; Gautel, M.; Oesterhelt, F.; Fernandez, J. M.; Gaub, H. E. Reversible unfolding of individual titin immunoglobulin domains by AFM. Science 1997, 276, 1109-1112.
