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GLP-1与2型糖尿病高血糖及临床处理 被引量:2

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摘要 胰高血糖素样肽-1(GLP-1)是一种肠促胰素,主要是由空肠末端、回肠、结肠上皮L细胞分泌,生理作用具有增强葡萄糖依赖性胰岛素分泌并促进胰岛素合成,同时降低胰高糖素水平,抑制食欲,延缓胃排空,通过多种途径参与血糖调控。随着GLP-1的多重效应不断被认识,以GLP-1为基础的药物-GLP-1受体激动剂和GLP-1类似物在2型糖尿病(T2DM)治疗中相继上市。
作者 冯玲 颜晓东
出处 《实用糖尿病杂志》 2015年第3期9-10,共2页 Journal of Practical Diabetology
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