不同海拔地区两种小型猪血液生理生化指标比较

Comparison of Blood Physiological and Biochemical Parameters of Two Kinds of Minipigs in Different Altitudes

本试验旨在比较高原蕨麻小型猪与平原巴马小型猪的血液生理生化指标差异,为高原蕨麻小型猪的实验动物化提供理论基础。试验分别在高原地区和西安市采集高原蕨麻小型猪与巴马小型猪血样,检测10项血液生理指标和14项血液生化指标,并对结果进行统计分析。结果显示,血液生理指标中高原蕨麻小型猪的红细胞计数(RBC)、血红蛋白(HGB)、红细胞压积(HCT)、红细胞平均血红蛋白含量(MCH)、红细胞平均血红蛋白浓度(MCMH)均极显著高于巴马小型猪(P<0.01),血小板(PLT)、红细胞分布列宽变异系数(RDW-CV)和红细胞分布宽度标准差(RDW-SD)与巴马小型猪相比差异显著(P<0.05);血液生化指标中高原蕨麻小型猪γ-谷氨酰基转移酶(GGT)、葡萄糖(GLU)、肌酐(CRE)均极显著高于巴马小型猪(P<0.01),其余指标均无显著差异(P>0.05)。结果表明,高原蕨麻小型猪具有低氧适应的生理特征,与巴马小型猪相比有独特的高原适应性,具有开发成为高原疾病动物模型的潜力。

This study was designed to compare the blood physiological and biochemical parameters between plateau Juema minipigs and plain Bama minipigs,and provide a theoretical basis for Jue- ma minipigs served as experimental animals in the future. The blood samples of Juema minipigs were taken in Gannan,and the blood samples of the Bama minipigs were taken in Xi＇an,24 blood physiological and biochemical parameters were tested using an automatic analyzer of blood cells and biochemistry. Between the plateau Juema minipigs and Bama minipigs, there were significant differences in PLT,RDW-CV and RDW-SD （P〈0.05） and extremely significant differences in RBC, HGB, HCT, MCH, MCMH, GGT, GLU and CRE （P〈0.01）. The plateau Juema minipig had an altitude acclimatization,so it was better than Bama minipig in plateau medical science.