单切口与双切口青白联合手术的临床疗效对比研究

The effect of one-site versus two-site phacotrabeculectomy in glaucoma patients with coexisting cataract

目的对比研究单切口与双切口青白联合手术治疗青光眼合并白内障的疗效。方法采用临床随机对照研究。选取52例(52眼)青光眼合并白内障患者随机分成两组:单切口组(白内障超声乳化联合人工晶体植入术和小梁切除术经同一切口完成)和双切口组(上方巩膜切口行小梁切除术和透明角膜切口行白内障超声乳化联合人工晶体植入术),每组各26例(26眼)。术后随访3个月6个月和12个月,比较两组患者眼压控制情况及视力情况。结果本研究最终完成随、访资料47例,其中单切口组23例和双切口组24例纳入分析。两组术后眼压均较术前明显降低,差异3个月、6个月和12个月有统计学意义(P 0.05);两组间术后3个月、6个月和12个月的眼压下降量比较,差异无统计学意义P(=0 5<.2,0.38和0.47)。两组间术后3个月、6个月和12个月的视力比较,差异无统计学意义(x^2=0.789,x^2=0.374;x^2=0.007,x^2=0.932;x^2=0.537,P=0.464)。结论单切口与双切口青白联合术均可安全、有效治疗青光眼合并白内障,两种术式具有相似疗效。

Objetive To compare the effect of one-site versus two-site phacotrabeculectomy in glaucoma patients with coexisting cataract. Methods It was a clinically randomized controlled trail. Fifty-two patients with glaucoma and cataract were randomly collected and evenly divided into two groups： one-site surgery and two-site surgery, 26 cases for each group. patients were followed up for 3、6 and 12 months. The mean intraocular pressure（IOP） and visual acuity were calculated between one-site and twosite Results one-site and phacotrabeculectomy. This study included complete postoperative data of 47 patients, of which 23 patients in 24 two-site surgerypatients in. There was a significant decline of IOP compared with pre-operation. There was no significant difference in mean IOP between the two groups at 3、6 and 12 months after surgery. There was no significant difference in between visual acuity the two groups at 3、6 and 12 months. Conclusions One-site and two-site phacotrabeculectomy can be a safe and efficacious surgery for treatment of glaucoma with coexisting cataract. There was no statistical significant difference in IOP control.