肝动脉介入化疗栓塞与射频消融联合治疗肝癌的研究分析

Hepatic Artery Interventional Chemotherapy Embolism With Radiofrequency Ablation for the Treatment of Liver Cancer Research Analysis

目的探讨经皮肝动脉介入化疗栓塞与射频消融联合治疗中、晚期肝癌的临床效果。方法选择56例中晚期肝癌患者,将患者分为肝动脉介入化疗栓塞与射频消融联合治疗组(A组)及单纯肝动脉介入化疗栓塞组(B组),每组28人,经治疗后,定期复查患者,比较两组患者血清甲胎蛋白浓度、肿瘤复发率及生存率情况。结果 A组患者非细胞毒性免疫抑制因子(AFP)浓度下降率为72.0%;复发率:7.14%;1年、2年、3年生存率分别为:87.0%、63.8%、40.1%;B组患者AFP浓度下降率为53.2%;复发率:25.00%;1年、2年、3年生存率分别为:65.2%、42.7%、28.5%。结论肝动脉介入化疗栓塞联合射频消融比单纯肝动脉介入化疗栓塞在治疗肝癌疾病上更加安全有效。

Objective To study the clinical efficacy of the percutaneous hepatic artery interventional chemotherapy embolism with radiofrequency ablation treatmentin advanced liver cancer.Methods Fifty-six cases of middle-late liver cancer patients were divided into hepatic artery interventional chemotherapy embolism with radiofrequency ablation treatment group（group A）and simple hepatic artery interventional chemotherapy embolism group（group B）,each group of 28 people,after treatment,serum concentration of AFP,tumor recurrence rate and survival rate were reviewed and compared.Results Patients in group A of AFP concentration decline rate was 72.0%,the recurrence rate 7.14%,1 year,2 years,3 years survival rate 87.0%,63.8%,40.1%,group B patients with AFP concentration decline rate was 53.2%. The recurrence rate 25.00%,1 year,2 years,3 years survival rate 65.2%,42.7%,28.5%.Conclusion The hepatic artery interventional chemotherapy embolism joint radiofrequency ablation is more safe and effective for the treatment of liver diseases.