奥美拉唑与雷贝拉唑对治疗十二指肠溃疡的临床疗效对比

Comparison of Clinical Treatment Effect on Duodenal Ulcer Between Omeprazole and Rabeprazole

目的：对比分析奥美拉唑与雷贝拉唑对治疗十二指肠溃疡的临床疗效。方法收集合江县人民医院及遂宁市第三人民医院2014年1月～2014年11月期间诊治的96例存在腹痛、反酸、嗳气、腹胀症状的十二指肠溃疡患者作为研究对象，将其分为两组后分别使用奥美拉唑（48例）与雷贝拉唑（48例）进行治疗，观察患者治疗第一天的腹痛缓解率、治疗后一周的反酸缓解率、嗳气缓解率、腹胀缓解率。结果雷贝拉唑组患者治疗第一天的腹痛缓解率、治疗后一周的反酸缓解率、嗳气缓解率、腹胀缓解率高于奥美拉唑组（P〈0.05）。结论雷贝拉唑对缓解十二指肠溃疡导致的临床症状，疗效优于奥美拉唑。

Objective Comparative analysis of clinical treatment effect on duodenal ulcer between omeprazole and rabeprazole.MethodsWe chose 96 duodenal ulcer patients cases of hejiang people＇s hospital and the third people＇s hospital of suining city with syptoms like abdominal pain,regurgitation,belching and abdominal distension from January 2014 to November 2014,divided the patients into two equal groups,one group were treated by omeprazoler and the other were treated by rabeprazole,observed the rate of abdominal pain remission in the first day,the regurgitation remission,the belching remission,the abdominal distension remission after a week of treatment.Results Under the treatment of rabeprazole,abdominal pain remission rate in the first day and the remission rate of acid regurgitation and abdominal distension remission rate after a week of treatment were higher than those of omeprazole（P〈 0.05）.ConclusionThe effect of rabeprazole on clinical remission of the symptoms of duodenal ulcer caused,curative is better than that of omeprazole.