超声骨密度测定对婴幼儿佝偻病早期诊断的价值研究

Value research of ultrasonicbone densitometry for early diagnosis of infantile rickets

目的：研究超声骨密度测定对婴幼儿佝偻病早期诊断的价值。方法全体0～3岁佝偻病患儿中，随机抽取50例0～1岁患儿纳入观察A组，抽取50例1～2岁患儿纳入观察B组，抽取50例2～3岁患儿纳入观察C组；从同期在本科门诊就诊的全体健康检查正常的婴幼儿中随机抽取50例0～1岁婴幼儿纳入对照A组，抽取50例1～2岁婴幼儿纳入对照B组，抽取50例2～3岁婴幼儿纳入对照C组。比较各年龄段观察组和对照组婴幼儿的超声骨密度测定值和观察组内男、女患儿的超声骨密度测定值以评价其早期诊断价值。结果观察A、B、C组患儿超声骨密度测定Z值明显低于对照A、B、C组，差异有统计学意义（P＜0.01）；观察组男、女患儿间超声骨密度测定Z值比较差异无统计学意义（P＞0.05）。结论超声骨密度测定仪对婴幼儿维生素D缺乏性佝偻病具有良好的诊断效果，值得在临床推广应用。

Objective To research the early diagnostic value of ultrasonic bone densitometry for infantile rickets.Methods Among all the 0～3-year-old children with rickets, there were 50 children aging 0～1 year old randomly taken into observation A group, 50 children aging 1～2 year old into observation B group, and 50 children aging 2～3 years old into observation C group. Random selection was also made among healthy children at the same period, and 50 of them aging 0～1 year old were divided into control A group, 50 children aging 1～2 years old were into control B group, and 50 children aging 2～3 years old were into control C group. Comparisons were made on measured values of ultrasonic bone densitometry in every group and different values in different gender, so as to evaluate its value for early diagnosis.Results The observation A, B and C groups had obviously lower Z value of ultrasonic bone densitometry than control A, B and C groups, and the difference had statistical significance （P〈0.01）. There was no statistically significant difference of Z value between male and female children in observation groups （P〉0.05）.Conclusion Ultrasonic bone densitometry can provide good diagnostic effect for infantile vitamin D deficiency rickets, and it is worthy of clinical promotion and application.