摘要
目的：探讨维生素D定量在心血管疾病诊断中的作用。方法：随机选取我院2009年3月至2013年4月收入的心血管疾病患者110例为研究对象，作为观察组，另取110例健康人为对照组，分别对两组血清25-羟基维生素D [25（OH） D]进行定量检测。结果：观察组患者血清25（OH）D的浓度≥30ng/ml的仅有7例，而对照组有101例，两组相比差异显著[χ^2=160.05；P〈0.01]；观察组中急性心肌梗死、不稳定性心绞痛、稳定性心绞痛、其他冠心病、心衰患者的血清25（OH） D定量结果比较无明显差异，无统计学意义（P〉0.05）；与对照组比较均明显较低，有统计学意义[t=19.75；P〈0.05]。结论：血清维生素D的浓度与心血管疾病的发生、发展呈负相关，临床可通过定量检测血清维生素D对心血管疾病进行辅助诊断。
Objective：To explore the role of Vitamin D in the diagnosis of cardiovascular disease. Methods：We randomly chose 110 patients as the observation group from those who received their treatment for cardiovascular disease in our hospital from March, 2009 to April, 2013, and we chose 110 healthy people as the control group. Then we detected quantitatively 25 （OH） D in each group.Results：In the observation group, only 7 cases 25 （OH） D are with over 30ng/ml while, 101 cases are with that level in the control group . There exists a great disparity between them （χ^2=160.05;P〈0.01）. In the observation group, the quantitative valueof 25 （OH） D of patients with the acute myocardial infarction, unstable angina, stable angina, other coronary heart diseases and congestive heart failure remain no obvious diferences and are of no statistic significance （P〉0.05）. In contrast, the quantitative valueof 25（OH） D in the control group are much higher and are of great statistic significance （t=19.75;P〈0.05）. Conclusions：There is a stro ng negative correlation between the concentration of vitamin D in the serum and the occurrence and progress of cardiovascular disease. Clinically, the quantitative testing of the vitamin D could be adopted to diagnose the cardiovascular disease.
出处
《医学检验与临床》
2015年第2期20-21,76,共3页
Medical Laboratory Science and Clinics
