露兜簕茎皮化学成分的研究

Chemical Constituents from the Stem Bark of Pandanus tectorius

目的研究露兜簕（Pandanus tectorius Soland.）茎皮的化学成分。方法采用硅胶柱色谱、Sephadex LH-20柱色谱、高效液相色谱分离化合物,通过理化数据测定和波谱技术分析确定所得化合物的结构。结果从露兜簕茎皮乙醇提取物中分离得到13个化合物,分别鉴定为3-hydroxy-2-isopropenyl-dihydrobenzofuran-5-carboxylic acid methyl ester（1）,松脂醇（2）,表松脂醇（3）,salicifoliol（4）,thero-2,3-bis-（4-hydroxy-3-methoxyphenyl）-3-ethoxypropan-1-ol（5）,erythero-2,3-bis-（4-hydroxy-3-methoxyphenyl）-3-ethoxypropan-1-ol（6）,eudesmin A（7）,黑麦草内酯（8）,松脂醇-4-O-β-D-葡萄糖苷（9）,原儿茶酸（10）,咖啡酸（11）,对羟基苯甲酸（12）和阿魏酸（13）。结论化合物1~13均为首次从该植物中分离得到。

OBJECTIVE To study the chemical constituents in the stem bark of Pandanus tectorius Soland. METHODS Compounds were isolated by repeated chromatography. Their structures were elucidated by spectroscopic methods. RESULTS Thirteen compounds were isolated and identified as 3-hydroxy-2-isopropenyldihydrobenzofuran-5-carboxylic acid methyl ester （ 1 ） , pinoresinol （2）, epi-pinoresinol （3）, salicifoliol （4）, thero-2, 3-bis- （4-hydroxy-3-methoxyphenyl） -3-ethoxypropan-l-ol （5）, erythero-2,3-bis- （4- hydroxy-3-methoxyphenyl） -3-ethoxypropan-1 -ol（ 6 ）, eudesmin A （ 7 ）, loliolide （ 8 ）, pinoresinol-4-O-β-D-glucoside （ 9 ）, protocatechuic acid（10）, caffeic acid（11）, p-hydroxybeuzoic acid（12）, and ferulic acid（13）. CONCLUSION All the compounds are isolated from this plant for the first time.