卵巢良性肿瘤剥除术后妊娠相关因素分析

Influencing factors of postoperative pregnancy in patients with benign ovarian tumor

目的分析卵巢良性肿瘤剥除术后的妊娠以及妊娠相关因素。方法回顾性分析行卵巢良性肿瘤剥除术并有生育要求、随访资料完整的141例患者的临床资料及术后妊娠率。结果 141例患者术后第1、2年累计妊娠率分别为58.16%和65.25%,低于正常人群,差异有统计学意义(P<0.05)。年龄≥35岁组的妊娠率低于年龄<35岁组,双侧肿瘤剥除术组低于单侧手术组,电凝止血组低于缝合止血组,不同体积的剩余卵巢组织妊娠率比较,差异有统计学意义(P<0.05);不同病理类型、肿瘤大小、手术途径的妊娠率比较,差异无统计学意义(P>0.05)。术后妊娠率与正常人群比较,差异无统计学意义。结论卵巢良性肿瘤剥除术后的妊娠率低于正常人群。年龄≥35岁、双侧卵巢手术、电凝止血及剩余卵巢组织体积大小是卵巢肿瘤剥除术后妊娠的影响因素。

[Objective] To investigate pregnancy rate and influencing factors after cystectomy in benign o- varian tumor patients. [Methods] A total of 141 patients with benign ovarian tumor who underwent cystecto- my were followed up to assess pregnant outcome. The clinical data were analyzed retrospectively. [Results] The postoperative pregnancy rate was 58.16% in the first year, the overall postoperative pregnancy rate within 2 years was 65.25%, they were significantly lower than those in normal population （P〈 0.05）. The pregnancy rate in the 35-year and older group was significantly lower than that in the under 35-year old group. The pregnancy rate in the bilateral surgery group was significantly lower than that in the unilateral surgery group. The pregnancy rate in the electric coagulation group was significantly lower than that in the suture hemostasis group. There were significant differences among different volumes of residual ovarian tissue （P〈 0.05）. However, the postoperative pregnancy rate had no correlation with histological type, tumor size or surgical approach. [Conclusions] Pregnancy rate in patients with benign ovarian tumor after cystectomy is lower than that in normal population. Age of 35 years or older, bilateral ovarian surgery, electric coagulation and the volume of residual ovarian tissue may influence the pregnancy ability.