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HR-HPV检测及宫颈液基细胞学检查对宫颈病变的筛查分析 被引量:1

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摘要 目的探讨分析HR-HPV检测、宫颈液基细胞学检查对宫颈病变筛查指标的影响。方法于我院门诊部进行近年来细胞学异常患者临床资料的收集,选取100例细胞学异常患者作为研究对象,全部患者均于阴道镜下进行活检,且实施HR-HPV检测,将病理结果作为标准,对比分析在宫颈病变中单独应用细胞学检测法、HR-HPV检测法和联合应用这两种检测方式的诊断价值。结果 100例患者中30例患者为NILM,45例患者为CINI,25例患者为CINⅡ~Ⅲ;经HRHPV检测,NILM患者中有7例患者为阳性,CINI患者中28例为阳性,CINⅡ~Ⅲ患者中12例为阳性;细胞学检测、HR-HPV检测以及联合两种检测方式在CINⅠ~Ⅲ敏感度的筛查上分别是56.5%、52.9%、50.6%,特异性分别是80.0%、80.0%、100.0%,其阴性预测值分别是98.5%、93.6%、100.0%。结论在宫颈癌筛查中,HR-HPV检测法和宫颈液基细胞学检查是两种有效可行的方法,两种方法联合应用可使诊断敏感度以及阴性预测值得到明显提高,但是不会增加其特异性。
作者 吴海明
出处 《中国医学工程》 2015年第3期137-137,共1页 China Medical Engineering
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