168例颈动脉斑块患者综合干预临床观察

168 Cases of Clinical Observation on Comprehensive Intervention in Patients with Carotid Artery Plaque

目的观察并分析不同类型的颈动脉斑块经生活方式干预、药物治疗后的效果。方法选取我院168例颈动脉单发斑块患者,按彩色多普勒超声检查斑块的回声强度进行分组,治疗上均给予抗血小板、降脂、控制血压血糖、饮食和运动干预等综合治疗,6个月后复查,评估不同回声的斑块的治疗效果。结果经过治疗,低回声斑块组和混合回声斑块组疗效相似,斑块总面积有明显缩小,差异有统计学意义(P<0.05),部分斑块回声出现改变;而等回声斑块组与强回声斑块组疗效相似,斑块总面积无明显变化,差异无统计学意义(P>0.05),斑块回声性质无变化。结论通过药物治疗和对动脉硬化高危因素进行干预,可以改变斑块性质,降低缺血性脑卒中的发病率。

Objective To observe the effect of different types of carotid atherosclerotic plaques by lifestyle intervention and drug treat-ment.Methods In our hospital 168 cases of solitary carotid plaque of patients, grouped by color ultrasound plaque echo intensity, treat-ment were given anti platelet, lipid, blood glucose, blood pressure control of diet and exercise intervention and other comprehensive treat-ment, 6 months after the review, assessment of therapeutic effect of different echo plaque.Results After treatment, low echo plaques group and mixed echo plaque group have similar efficacy, total plaque area is significantly reduced, the difference was statistically significant, some of the plaque echo appeared to change;and the equal echo plaque group similar to the strong echo of plaque group curative effect, the total plaque area had no obvious change, no statistically significant difference, plaque echo not change.Conclusion Drug treatment and intervention on atherosclerosis risk factors, can change the plaque, reduce the incidence of cerebral arterial thrombosis.