脑梗死中医证型与血清CRP含量、临床神经功能缺损积分的关系研究

Research on the relationships between the TCM syndrome of cerebral infarction and serum CRP levels, clinical neurologic deficit score

目的:研究脑梗死中医证型与血清CRP含量、临床神经功能缺损积分的关系。方法:依据中医辨证分型方法,将64例患者均分为痰证组和非痰证组,另取体检健康合格30例作为对照组,进行临床神经功能缺损程度评分,同时在患者发病12h内,吸取其指末微量血液,采用散色比浊法测定血清CRP含量,比较分析临床神经功能缺损程度评分、CRP含量与脑梗死中医证型的关系。结果:脑梗死痰证患者的临床神经功能缺损积分、血清CRP含量显著高于非痰证患者,差异显著;同时2种不同脑梗死中医证型患者的CRP含量也显著高于正常对照组,差异显著。结论:不同中医证型的脑梗死患者临床神经功能缺损积分以及血清CRP含量均不同,同时与健康者具有极显著的差异,可以将这两项指标作为临床诊断脑梗死中医证型的客观指标。

Objective： To study the cerebral infarction TCM syndrome type and the content of CRP in serum, clinical neural function defect integral relationship. Methods： According to TCM syndrome differentiation method, 64 patients were divided into phlegm syndrome group and non-phlegm syndrome group, another healthy qualified 30 cases as control group, compared the clinical neurological deficit scores, also in the pathogen of 12h patients, and absorb the refers to the end of the trace of blood. Serum CRP concentration was measured using color scattering ratio the relationship between turbidity method, comparative analysis of the clinical neurological deficit scores. The content of CRP in cerebral infarction and TCM syndrome type. Results： The content of serum CRP in patients with cerebral infarction clinical neural function defect of phlegm syndrome integral, significantly higher than non-phlegm syndrome patients, significant difference; At the same time, CRP content in 2 kinds of different TCM type of patients with cerebral infarction is significantly higher than that of the normal control group, the difference was significant. Conclusion： The patients with cerebral infarction of different TCM syndrome types of clinical neural function defect score and serum CRP contents were different, at the same time and normal healthy subjects have significant differences, can these two indicators as the objective index for clinical diagnosis of cerebral infarction and TCM syndrome type.