电视胸腔镜胸膜固定术和胸腔闭式引流术治疗恶性胸腔积液的效果比较

Clinical effect between the video-assisted thoracoscope pleurodesis and thoracic closed drainage on patients with malignant pleural effusion

目的:比较电视胸腔镜胸膜固定术和胸腔闭式引流术治疗恶性胸腔积液的临床疗效。方法:将110例恶性胸腔积液患者分为研究组和对照组各55例,研究组采用电视胸腔镜胸膜固定术治疗,对照组采用胸腔闭式引流术治疗。综合比较两组患者临床缓解率,治疗前后胸腔积液蛋白定量、白细胞及乳酸脱氢酶的改善情况。结果:研究组临床缓解率为92.7%,高于对照组的78.2%(P<0.05);研究组治疗后蛋白定量、白细胞及乳酸脱氢酶改善情况均显著优于对照组(P<0.05)。结论:电视胸腔镜胸膜固定术治疗恶性胸腔积液疗效显著,在改善胸腔积液总蛋白定量、白细胞及乳酸脱氢酶方面优于胸腔闭式引流术。

Objective：To compare the clinical effect of video-assisted thoracoscope pleurodesis and thoracic closed drainage on patients with malignant pleural effusion.Methods：110cases of malignant pleural effusion patients were randomized into the research group and the control group,each were included 55 cases.The research group were treated with video-assisted thoracoscope pleurodesis,while the control group were with thoracic closed drainage.The remission rate,pleural effusion protein quantitativeness before and after the treatment,and the improvement of leukocyte and lactic dehydrogenase of both groups were compared.Results：The remission rate of the research group（92.7%）was higher than that of the control group（78.2%）,P〈0.05.The pleural effusion protein quantitativeness before and after the treatment,and the improvement of leukocyte and lactic dehydrogenase in the research group were significantly superior to those of the control group（P〈0.05）.Conclusion：The video-assisted thoracoscope pleurodesis is more effective in treating malignant pleural effusion.It＇s better than the thoracic closed drainage in improving pleural effusion leukocytes and lactic dehydrogenase.