外科重症监护室临床细菌分布及耐药性监测

Clinical bacteria distribution and drug resistance surveillance in surgical intensive care unit

目的:讨论分析重症监护室中临床细菌的临床分布情况与耐药特性。方法:对临床分离的300株菌株,根据革兰阳性球菌与革兰阴性杆菌实施分类,且依照统一方案实施抗菌药物药敏试验。结果:300株菌株中,来自痰液的菌株标本为152株(50.7%),来自血液的菌株标本为56株(18.7%),来自尿液的菌株标本为52株(17.3%),来自粪便与伤口分泌物的菌株标本为40株(13.3%)。同时,对大肠埃希菌、鲍曼不动杆菌与克雷伯菌对抗生素具有的耐药率进行分析研究,其中大肠埃希菌耐药率最差的为头孢他啶(43.9%);克雷伯菌耐药率最差的为亚胺培南(54.4%);而鲍曼不动杆菌耐药率最差的为哌拉西林(47.8%)。结论:细菌耐药性呈现着持续增长的趋势,对高危人群与高危病区需加强有效监测。

Objective：To investigate and analyze the bacteria distribution and drug resistance surveillance in surgical intensive care unit（ICU）.Methods：300strains of clinical isolated bacterial strains were classified according to the gram-positive bacteria and gram negative bacillus,and antibiotic drug susceptibility test was implemented in accordance with the unified plan.Results：Of the 300 strains of clinical isolated bacterial strains,152 strains were from sputum specimens（50.7%）,56 strains from blood specimens（18.7%）,52 srrains from urine specimens（17.3%）and 40 strains from human feces and wound secretions（13.3%）.The research results of drug resistance rate of escherichia coli,acinetobacter baumannii and klebsiella showed that their worst drug resistance rate were ceftazidime（43.9%）,imipenem（54.4%）and piperacillin（47.8%）respectively.Conclusion：The bacterial resistance takes on the rising trend,so the effective surveillance should be strenghened in high-risk population and high-risk wards.