药物预处理对预防依托咪酯诱发肌颤的研究进展

Research progress of pharmacological preconditioning in preventing muscle tremor induced by etomidate

依托咪酯作为非巴比妥类静脉短效催眠药被广泛用于临床麻醉,但可诱发肌颤,研究表明肌松药、阿片类药物、右美托咪定、咪达唑仑和硫酸镁等对肌颤的发生均有预防作用,笔者将依托咪酯诱发肌颤的机制及治疗进展进行综述。

Etomidate,a kind of nonbarbiturates intravenous short-acting hypnotic drug,has been widely-used in clinical anesthesia,but it can induce muscle tremor.Researches show that muscle relaxant,opioids,dexmedetomidine,midazolam,magnesium sulfate,and the like,have the preventive effect on muscle tremor.The article reviews the pathogenesis of muscle tremor induced by etomidate and its treatment progress.