摘要
Rho/Rho激酶信号通路参与调节细胞的收缩、黏附、迁移、增殖、凋亡等多种生物学行为和功能,随着对Rho/Rho激酶信号通路研究的深入,发现其在急性肺损伤/急性呼吸窘迫综合征中发挥着重要的作用。笔者就Rho/Rho激酶信号通路在急性肺损伤/急性呼吸窘迫综合征中的作用机制作一综述。
Rho/Rho-kinase signaling pathway regulates lots of biological cellular functions,such as contraction,adhesion,migration,proliferation and apoptosis.With the further study of Rho/Rhokinase signaling pathway,we found that it played an important role in acute lung injury（ALI）and acute respiratory distress syndrome（ARDS）.This article reviews the role of Rho/Rho-kinase signaling pathway playing in the mechanism of action in ALI and ARDS.
出处
《华夏医学》
CAS
2015年第2期121-124,共4页
Acta Medicinae Sinica
关键词
RHO
RHO激酶
急性肺损伤
急性呼吸窘迫综合征
Rho/Rho associated kinase （ROCK）, acute lung injury （ALI）, acute respiratory distress syndrome （ARDS）
