回族因素对老年患者术后认知功能障碍发生的影响

Effect of Hui nationality on development of postoperative cognitive dysfunction in elderly patients

目的评价回族因素对老年患者术后认知功能障碍（POCD）发生的影响。方法择期全麻下行胸部、腹部或骨科手术的老年患者425例，年龄65～75岁，体重50一85kg，ASA分级I或Ⅱ级，根据民族分为2组：回族组（n=209）和汉族组（n=216）。分别于术前1d和术后3～7d时采用简易精神状态量表（MMSE）评分评估认知功能，术后MMSE评分较术前下降4分及以上即为发生POCD，记录POCD的发生情况。结果回族组POCD发生率（33．0％）与汉族组POCD发生率（30．5％）比较差异无统计学意义（P〉0．05）。结论回族因素不会影响老年患者POCD的发生。

Objective To evaluate the effect of Hui nationality on postoperative cognitive dysfunction （POCD） in elderly patients. Methods Four hundred and twenty-five patients, aged 65-75 yr, weighing 50-85 kg, of ASA physical status I or II , scheduled for elective thoracic, abdominal or orthopedic surgery under general anesthesia, were enrolled in the study. According to the nationalities, they were divided into Hui nationality group （Hui group, n = 209） and Han nationality group （Han group, n= 216）. Cognitive function was evaluated using Mini-Mental State Examination （MMSE） at 1 day before operation and 3-7 days after operation. The patients were diagnosed as having POCD if postoperative MMSE scores decreased by ≥ 4 compared with that before operation. The development of POCD was recorded in Hui and Han nationalities. Results There were no significant differences in the incidence of POCD between Hui group （33.0%） and Han group （30.5%）. Conclusion Hui nationality dos not affect the development of POCD in elderly patients.