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美托洛尔治疗慢性充血性心力衰竭的临床分析

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摘要 目的探讨美托洛尔在慢性充血性心力衰竭治疗中的临床价值。方法收集78例慢性充血性心力衰竭患者,随机分为美托洛尔组(39例)和对照组(39例),对照组予常规治疗,观察组在此基础上加用美托洛尔。分别统计2组治疗3个月后心率(HR)、收缩压(SBP)、舒张压(DBP)、左心室舒张末期内径(LVEDd)、左心室射血分数(LVEF)的变化,并根据NYHA分级标准对心功能改善情况进行评估。结果 2组心率、血压均较治疗前下降,但观察组下降幅度更大,2组相比差异有统计学意义(P<0.05);观察组治疗后左心室舒张末期内径较治疗前明显下降,而对照组无显著差异;2组治疗后左心室射血分数均上升,观察组上升幅度更大,差异有统计学意义(P<0.05)。2组心功能改善情况:观察组总有效率为89.74%,高于对照组的66.67%,差异有统计学意义(P<0.05)。结论在常规治疗的基础上应用β2受体阻滞剂美托洛尔能改善充血性心力衰竭患者的心率、血压及心功能,提高左心室射血分数,疗效显著,值得临床推广应用。
作者 李洁荣 吕云
出处 《基层医学论坛》 2015年第17期2318-2319,共2页 The Medical Forum
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