麻杏石甘汤加减治疗小儿病毒性肺炎50例临床观察

Clinical observation of modified Maxinshigan Decoction in the treatment of 50 cases of viral pneumonia in children

目的观察麻杏石甘汤加减治疗小儿病毒性肺炎的临床疗效。方法选取2010年3月至2014年3月在我院接受治疗的病毒性肺炎患儿100例,随机分为治疗组和对照组各50例,治疗组采用麻杏石甘汤加减治疗,对照组采用利巴韦林注射液和阿奇霉素联合治疗。7 d为1个疗程,2个疗程后比较2组的临床疗效,并对患儿以及患儿家属进行问卷调查。结果治疗组咳嗽消失、啰音消失以及胸片恢复时间均显著短于对照组,2组比较差异有统计意义(P<0.05);治疗组总有效率为92.0%,对照组为74.0%,2组比较差异有统计意义(P<0.05);治疗组满意率为80.0%,对照组为52.0%,2组比较差异有统计意义(P<0.05)。结论麻杏石甘汤加减治疗小儿病毒性肺炎可以有效缩短病程,提高疗效,增加患儿的满意度,且无明显不良反应,值得在临床上推广应用。

Objective To investigate the clinical efficacy of modified Maxinshigan Decoction in the treatment of viral pneumonia in children. Methods 100 cases of children with viral pneumonia treated in our hospital from March 2010 to March 2014 were randomly divided into a treatment group and a control group, 50 cases each. The treatment group were given Maxinshigan Decoction and the control group were given Ribavirin Injection combined with Azithromycin, 7 days for a course of treatment. The clinical efficacy of the two groups were compared after two courses, and a questionnaire survey of children and their families was conducted. Results The disappearing time of cough symptoms and pulmonary rales and chest X-ray absorption recovery time in the treatment group were significantly shorter than those in the control group, and the difference between the two groups was statistically sig- nificant （P〈0.05）. The overall response rate of the treatment group was 92.0% and that of control group was 74. 0%, the difference of the two groups was highly statistically significant （P〈0.05）. The satisfaction rate in treat- ment group was 80.0% and that in the control group was 52.0%, the difference between the two groups was statis- tically significant （P〈0.05）. Conclusion When treating children with viral pneumonia, moddified Maxinshigan Decoction can effectively shorten the course, improve the efficacy and increase patients＇ satisfaction, without sig- nificant adverse reactions, worthy of clinical application.