依达拉奉注射液对急性脑梗死患者血清C反应蛋白水平和功能恢复的影响

The effect of edaravone injection in restoring to the normal level the serum C-reactive protein and other functions of patients of acute cerebral infarction

目的探讨依达拉奉注射液对急性脑梗死患者血清C反应蛋白水平和各项功能恢复的影响。方法回顾性分析80例急性脑梗死患者临床治疗资料,其中对照组40例患者,采用临床常规手段治疗,观察组40例患者,在常规组患者治疗的基础上给予依达拉奉注射治疗,比较两组患者治疗前、治疗后1周和2周的血清C反应蛋白水平,神经功能缺损评分以及日常生活能力评级。结果治疗前两组急性脑梗死患者的血清C反应蛋白水平差异不显著(P>0.05);治疗后,观察组患者的血清C反应蛋白水平、神经功能缺损程度显著低于对照组(P<0.05),日常生活活动能力评分显著高于对照组(P<0.05)。结论依达拉奉注射液可有效降低急性脑梗死患者血清C反应蛋白的水平,显著改善患者的神经功能缺损症状,进而提高患者日常生活活动能力。

Objective To the effect and mechanism of edaravone injection in restoring to the normal level the serum C-reactive protein and other functions of the patients of acute cerebral infarction.Method 80 patients with acute cerebral infarction were randomly divided into an experimental group and a control group.The control group treated with conventional medicine while the experimental group were treated with edaravone injection in addition to the conventional medicine as provided to the control group.The data of the serum C-reactive protein levels of both groups as obtained both one and two weeks before and after treatment were compared.The neural functions and day-to-day living abilities of both groups were also evaluated.Findings The difference in the level of serum C-reactive protein between the two groups before treatment was not statistically significant （P 〉0.05）.After treatment, the level of serum C-reactive protein and the impairment of neural function of the experimental group were both significantly lower than those as observed in the control group （P 〈0.05）.The day-to-day living abilities of the experimental group was also significantly higher than those of the control group as observed after treatment （P 〈0.05）.Conclusion Edaravone injection as a medicine can effectively lower the level of serum C-reactive protein and restore the neural function of the patients with acute cerebral infarction and hence improve general day-to-day living abilities of the patients.