摘要
脑卒中后抑郁(PSD)是脑卒中后常见的神经精神并发症。其发病机制尚未完全明确,涉及脑卒中后的神经生物学改变和心理应激障碍,而且相关因素复杂,研究表明PSD与高血清胆红素、血清糖化血红蛋白水平低及痴呆评定量表评分减低、血糖水平升高、维生素B12缺乏、低水平的高密度脂蛋白相关,患者的临床表现及诊断缺乏特异性,在治疗方面,以药物治疗为主,辅以心理治疗等其他治疗方法。目前对于PSD的相关问题尚需进一步研究。
Post-stroke depression（PSD） is a common neuropsychiatric complication after stroke.The pathogenesis is not fully clear yet,which involves the neuronal biological factors and psychological stress dis-orders after stroke,and the related factors are complex.Recent studies have shown that PSD is associated with high serum total bilirubin,low serum levels of glycosylated hemoglobin and lower MDRS I/P scores,high serum levels of glucose,vitamin B12 deficiency and low levels of HLD.The clinical manifestations and diagnosis are lack of specificity.As for the treatment, drug treatment is the major method,supplemented by other treat-ments such as psychotherapy.Further study is still needed for the PSD related problems.
出处
《医学综述》
2015年第11期2005-2007,共3页
Medical Recapitulate
关键词
脑卒中后抑郁
脑卒中
脑血管病
抑郁
Post-stoke depression
Stroke
Cerebrovascular diseases
Depression
